Results 51 to 60 of about 157,915 (311)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
HeritageCanada’s heritage sites, while fewer in number compared to Europe, face significant challenges in accessibility due to strict preservation laws. Many were built before social inclusion became a priority, making them difficult to navigate for individuals ...
Maryem Lakoud +6 more
doaj +1 more source
Supramolecular architecture of a multi-component biomimetic lipid barrier formulation
Journal of Colloid and Interface Science, 2021 Biomimetic liquid crystalline systems are widely used in skin care cosmetics and topical pharmaceutical preparations. Our ability to rationally design such formulations, however, is hampered by our incomplete understanding of their structure on the nanoscale.Using polarized light microscopy and small-angle and wide-angle X-ray scattering, the molecular
Delaram Ahmadi +10 more
openaire +6 more sources
Distribution of discontinuous mudstone beds within wave-dominated shallow-marine deposits : Star Point Sandstone and Blackhawk Formation, Eastern Utah [PDF]
, 2014 Acknowledgements Funding for this study was provided from the Research Council of Norway through the Petromaks project 193059 and the FORCE Safari Project. The lidar data was collected by Julien Vallet and Samuel Pitiot of Helimap Systems SA.
Buckley, Simon +2 more
core +2 more sources
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
An overview of virtual city modelling : emerging organisational issues [PDF]
, 2007 This paper presents a recent overview of the increasing use of Virtual Reality (VR) technologies for the simulation of urban environments. It builds on previous research conducted on the identification of three-dimensional (3D) city models and offers an ...
Horne, Margaret +2 more
core
RPPM : Rapid Performance Prediction of Multithreaded workloads on multicore processors [PDF]
, 2019 Analytical performance modeling is a useful complement to detailed cycle-level simulation to quickly explore the design space in an early design stage. Mechanistic analytical modeling is particularly interesting as it provides deep insight and does not ...
Akram, Shoaib +3 more
core +2 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
PARC: Pesquisa em Arquitetura e Construção, 2014 This paper presents an analysis of the Building Information Modeling implementation process in architectural and industrial design companies in Belo Horizonte.
Miguel Pereira Stehling +1 more
doaj +1 more source