Results 61 to 70 of about 1,606,724 (205)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Architectural design principles and processes for sustainability : Towards a typology of sustainable building design [PDF]

open access: yes, 2011
The shift towards sustainable buildings requires a transformation of the architectural design process. This paper examines how sustainability is embedded into design methodology and mapped onto, or has transformed, the design process in practise ...
Grierson, David, Moultrie, Carolyn Mary
core   +3 more sources

Actors and Vehicles of Architectural Criticism (7)

open access: yes, 2016
The 1924 Form and Color show and the Critique of Architecture Criticism Mathilde Simonsen Dahl Oslo Centre for Critical Architectural Studies (OCCAS-AHO) For the very first issue in the Norwegian architectural journal Byggekunst in 1919 art historian ...
Mapping Architectural Criticism
core   +1 more source

Exploring Metaverse Integration in Architectural Education for Immersive Learning and Creativity [PDF]

open access: yesComputer and Knowledge Engineering
In response to the evolving demands of architectural education in the digital age, this study explores the transformative potential of the metaverse as a pedagogical platform.
Mahdi Motamedmanesh   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Towards Circularity: A Qualitative Study of Circularity Adoption in Australian Architectural Practice

open access: yesArchitecture
This qualitative research investigates the adoption of Circular Economy (CE) principles in contemporary Australian architectural practice, referred to as circularity, to address climate change, resource scarcity, and increasing demands for built ...
Christopher Bamborough   +8 more
doaj   +1 more source

BIM2BEM integrated approach: Examining status of the adoption of building information modelling and building energy models in Egyptian architectural firms

open access: yesAin Shams Engineering Journal, 2018
Egyptian architectural firms are moving from the use of CAD towards the adoption of BIM. Meanwhile, these firms are challenged with the use of BEM in order to cope with the call for energy conservation.
Laila Mohamed Khodeir, Ashraf Ali Nessim
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Research on Pathology Information Management of Educational Architectural Heritage Based on Digital Technology: The Case of James Jackson Gymnasium

open access: yesBuildings
Rapid advances in technology have led to an increasing demand for this type of information in the field of cultural heritage and architectural conservation.
Hechi Wang   +6 more
doaj   +1 more source

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