Results 111 to 120 of about 436,555 (285)

Quantitative Comparison of Geographical Color of Traditional Village Architectural Heritage Based on K-Means Color Clustering—A Case Study of Southeastern Hubei Province, China

open access: yesBuildings
The architectural heritage of traditional villages, as an important bearing entity of regional culture, contains strong regional color attributes. However, under the wave of contemporary rapid economic development, the color of traditional village ...
Li Dong, Meiqi Kang
doaj   +1 more source

Representation of National Identity in Malaysian State Mosque Built Form as a Socio- cultural Product

open access: yesInternational Journal of Built Environment and Sustainability, 2018
The formation of national identity is the essence for a multi-racial country like Malaysia because it can strengthen national solidarity, create a common aspiration, and sustain the continuity of a historical heritage with multiple ethnicity and ...
Alice Sabrina Ismail
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

The effects of 12 weeks of static stretch training on the functional, mechanical, and architectural characteristics of the triceps surae muscle-tendon complex. [PDF]

open access: yesEur J Appl Physiol, 2021
Longo S   +8 more
europepmc   +1 more source

Mirroring or misting: On the role of product architecture, product complexity, and the rate of product component change [PDF]

open access: yes, 2015
This paper contributes to the literature on the within-firm and across-firm mirroring hypothesis – the assumed architectural mapping between firms’ strategic choices of product architecture and firm architecture, and between firms’ architectural choices ...
Burton, Nicholas
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

A Study on Architectural Type and Design Characteristics of Floating Architecture [PDF]

open access: yesJournal of Korean navigation and port research, 2011
†Professor, Department of Architecture & Building Engineering, Kunsan National University, Gunsan 573-701, Korea 요 약 :플로팅건축물은 최근 지구온난화에 따른 해수면의 상승, 소득 증대 및 관광행태 변화에 따라 급증한 해양 레포츠 수요에 대응하는 효과적인 건축물이다. 국내 플로팅건축은 이미 전문회사들이 등장한 유럽과 비교하여 초보적인 도입기 이다. 플로팅건축은 프로그램, 형태, 건축규모, 층수, 위치, 접근방법, 이동성, 에너지 자립도 등 8가지 기준에 따라 유형 구분이 가능하다.
openaire   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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