Results 61 to 70 of about 63,712 (264)
Aesthetics in architecture: unity of form, function and meaning
Trans/Form/AçãoIn modern architectural design, “formal beauty” and “functional beauty” have become a new concept. At present, architects have gradually attached importance to the functional and aesthetic aspects of architecture in contemporary architectural design ...
Fangyu Cheng
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Architecture of the Churches Dedicated to St. Hieronymus in Slovenia
Edinost in Dialog, 2020 The article discusses the architectural features of the churches, dedicated to St. Hieronymus. Particular attention is paid to the characteristics in which their association with the patron can be identified. The research is set in two steps.
Leon Debevec
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Characteristics of Enterprise Architecture Analyses [PDF]
Proceedings of the Sixth International Symposium on Business Modeling and Software Design, 2016 Rauscher, Julia +2 more
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Suitability Evaluation of Architectural Images Built in Communities Based on the Niche-Fitness Model
BuildingsArchitectural images, experienced visually and spatially, embody urban culture, aesthetics, and identity, yet their suitability in urban communities remains underexplored.
Wenjun Peng +4 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Research on the Application of Architectural Decoration Materials in Interior Design [PDF]
E3S Web of ConferencesAs an important part of the interior design, the architectural decoration materials can effectively improve the effect of the interior design, and make the interior design to meet people’s aesthetic needs.
Sheng Fan
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source