Results 41 to 50 of about 34,382 (305)

Creating the Belgrade waterfront identity through a prism of architecture and urban planning competitions [PDF]

open access: yesSpatium, 2017
The architecture and urban planning competitions are a form of architectural activity that bring creative ideas important for parts of cities or territories, and they can precede the creation of future planning documentation.
Petrović-Balubdžić Miroslava
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Designer buildings: an evaluation of the price impacts of signature architects [PDF]

open access: yes, 2009
This study investigates whether commercial offices designed by signature architects in the United States achieve rental premiums compared to commercial offices designed by nonsignature architects.
Fuerst, Franz   +2 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Entstaatlichung lokaler öffentlicher Dienstleistungserbringung in der Europäischen Union [PDF]

open access: yes, 2001
This article deals with issues related to theory/practice and professionals/layman in architectural competitions. The data is based from experience in Finland.
Kazemian, Reza, Rönn, Magnus
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Architectural Competitions for Care and Caregiving

open access: yes, 2016
This article will discuss architecture and architectural competitions that are related to ageing populations of the modern welfare society. The emphasis lies on the need for new buildings for care and caregiving. The realization of these buildings demonstrates beliefs and notions about the appropriate interaction between the human being and ...
Rönn, Magnus, Andersson, Jonas E
openaire   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

The Olympic Buildings as a new typology for architects and engineers [PDF]

open access: yes, 2008
Integration between Architecture and Engineering is one of the cardinal elements of the IASS activities and is generally perceived either as a ‘starting point’, being a quality of the ancient Master Builders of Medieval and Renaissance times or as a ...
Cresciani, M.
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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