Results 91 to 100 of about 54,654 (304)

Research on the application status and countermeasures of traditional architectural elements in architectural environment design [PDF]

open access: yesSHS Web of Conferences
Traditional architectural elements carry our excellent traditional culture, contain rich connotation, and are the valuable wealth of modern architectural environment design research and reference.
Yuan Yifan, Ren Hao
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Portmerion, Proportion and Perspective [PDF]

open access: yes, 2012
The holiday village of Portmerion was created by Bertram Clough Williams-Ellis (1883 1978) over a period of fifty-one years, starting in 1926. It was grade II listed in 1971.
Messer, Sebastian, Ellis, Francis
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

The Effect of Cultural Factor on the Architectural Characteristics of the Traditional Houses Traditional Houses in Sulaymaniyah City (1900-1940), as case study

open access: yesSulaimani Journal for Engineering Sciences
Culture and cultural changes have influenced architectural form throughout the ages, especially for residential houses, transforming their shape and content. This is due to a significant change in cultural heritage, values, customs, and traditions.
كاني محمد محمد صالح   +1 more
doaj   +1 more source

Architecture firms and their cultures

open access: yesRevista Gestion I+D, 2022
Le bureau d’architecture est un groupe d’architectes et parfois d’autres professionnels et techniciens qui ont 2 fonctions : (1) être une plate-forme qui socialise l’exercice individuel ; (2) positionner la pratique professionnelle devant la société.
openaire   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Inventory

open access: yesFootprint, 2014
What is the value, now, in conducting historical research into architectural ideas? The paper addresses the function of contemporary PhD research in light of a) the so-called historiographical turn in architectural history, theory and criticism research ...
Andrew Leach
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

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