Results 31 to 40 of about 18,497 (299)

Manufacturing urbanism: an architectural practice for unfinished cities [PDF]

open access: yes, 2012
This PhD is a reflection upon an architectural practice developed over twelve years, incorporating architectural design, teaching and writing. The practice consists of a variety of projects ranging from full-scale architectural interventions to ...
Gretchen Wilkins
core  

Encountering drawing

open access: yes, 2023
This project report outlines the research-led exhibition, Drawing Room – part of an ongoing collaborative design research project focusing on drawing – exhibited at Toi Moroki Centre of Contemporary Art Christchurch (CoCA), New Zealand.
Macken, Marian   +5 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Evaluating relationships between hand-drawing ability and design performance: Case of Architecture Study Program UGM

open access: yesARTEKS : Jurnal Teknik Arsitektur
The importance of drawing is among the most common discourses in architectural practice and education. Current research investigating the relation between drawing ability and architecture students’ study performance give various results, indicating that ...
Mario Lodeweik Lionar   +5 more
doaj   +1 more source

Drawing as Epistemic Practice in Architectural Design

open access: yesFOOTPRINT, 2010
The essay deals with drawing as a genuine form of knowledge in architectural design. Drawing is described as an epistemic practice enmeshed with historically changing, material spaces of knowledge. Starting with a brief examination of historic philosophical positions on the epistemicity of drawing, the essay tries to sketch out a tentative heuristic ...
openaire   +2 more sources

Integrating Sustainable Manufacturing into Architectural Design Teaching through Architectural Design Competitions

open access: yes, 2023
Sustainable manufacturing is essential for boosting resource allocation efficiency, as well as sustainable economic development, while the construction industry is one of the main sectors affecting it.
Xiaolong Yang   +5 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

The story of mediterranean’s living. Narration and project in Ponti’s "ideario" of architecture

open access: yesFestival dell'Architettura Magazine, 2019
The essay comes from a reflection on narrative structures of architectural project. It is dedicated to architecture domestic Mediterranean in the work of Gio Ponti.
Lucia Miodini
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Analyzing Architectural Drawing in the Works of Four Contemporary Chinese and Japanese Architects: A Multi-Dimensional Approach

open access: yesArchitecture
In the image era, architectural drawing gradually evolved from being a part of traditional architectural design to an artistic form with independent aesthetic value. However, a systematic evaluation method for this unique art form is still lacking.
Lei Tan, Tomoyuki Tanaka, Jiahao Liu
doaj   +1 more source

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