Results 51 to 60 of about 368,153 (290)

Educating children in Architecture: XXth architectural narratives troughs toys design [PDF]

, 2014
Ponencia presentada a Session 2: La infancia en el medio ambiente urbano / The urban childTeaching processes are, since renaissance, created and supported in order to develope specifically skills for a small part of the society.
Ginoulhiac, Marco
core  

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Mediating Cognitive Transformation with VR 3D Sketching during Conceptual Architectural Design Process [PDF]

, 2011
Communications for information synchronization during the conceptual design phase require designers to employ more intuitive digital design tools. This paper presents findings of a feasibility study for using VR 3D sketching interface in order to replace
B. Abdullah, Muhamad Taufik, B. Hj Jaafar, Mohd Saleh, Ibrahim, Rahinah, Pour Rahimian, Farzad, Wirza Binti O. K. Rahmat, Rahmita   +4 more
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A Model of Architectural Design Education Based on Collaborative and Interactive Thoughts [PDF]

Fanāvarī-i āmūzish, 2019
Background and Objective:The large gap between academic lessons in architecture schools and the labor market in society has made many graduates of architecture schools unfamiliar with the work process and solving architectural issues in society.
E. Lalbakhsh, V. Ghobad, S. Azizi
doaj   +1 more source

Structures of policy : Building Bulletin in Postwar Britain [PDF]

, 2016
School design in Great Britain underwent great typological change in the post-war era, necessitated by depleted construction labour and materials, coupled with a bourgeoning school-age population resulting from the population boom and an expanded student
Lang, Ruth
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Architectural students' year-out training experience in architectal offices in the UK [PDF]

, 2015
This paper investigates architectural students’ ‘year-out’ learning experiences in architectural offices after completing RIBA Part I study within a UK university.
Gao, Yun, Orr, Kevin
core  

The role of virtual reality in built environment education [PDF]

, 2008
This study builds upon previous research on the integration of Virtual Reality (VR) within the built environment curriculum and aims to investigate the role of VR and three-dimensional (3D) computer modelling on learning and teaching in a school of the ...
Alvarado R. G., Ausburn L. J., Denscombe M., Horne M., Knight P., Mantovani F., Stone R.   +6 more
core   +2 more sources