Results 91 to 100 of about 13,395,687 (337)

Changing the Architectural Profession - Evidence-Based Design, the New Role of the User and a Process-Based Approach [PDF]

open access: yes, 2007
The construction industry is characterised by ever-changing projects that constantly involve new clients, teams and people. This results in the need to build up new sets of relationships each time.
Budgen, A.   +3 more
core  

Perceptual and Visual Void on the Architectural Form: Transparency and Permeability

open access: yes, 2012
Form, space and voids are the basic elements used in architectural design process. In this paper, the concept of void is addressed in relation to the architectural form.
N. Kuloğlu, Tülay Şamlıoğlu
semanticscholar   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Parametric Creative Design of Building Free-forms Roofed with Transformed Shells Introducing Architect’s and Civil Engineer’s Responsible Artistic Concepts

open access: yesBuildings, 2019
The article concerns a parametric description of unconventional building forms roofed with folded sheeting transformed elastically into shells. The description supports the designer in the search for attractive forms and a rational use of materials.
Jacek Abramczyk, Aleksandra Prokopska
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Commitment to Excellence in the New: Revival of the Notion of "the Fine” for Comprehension of the Dialogue between Artistic Image and Intellectual Idea in a Modern Architectural Form

open access: yesПроект Байкал, 2016
The revival of the notion of "the fine" has become one of the tasks in the framework of matching historical and theoretical issues related to architectural criticism at the present stage of architectonic thinking integration into the space of a non ...
Yuri Volchok
doaj   +1 more source

The theory on the construction of an architectural form created Juliusz Żórawski as “tool of architectural communication”. [PDF]

open access: yes, 2017
Ponència presentada a: Session 3: Laboratorios de diseño innovador basado en la interacción humana / Laboratories for human centered innovative design ...
Bocheńska-Skałecka, Anna
core  

Ambiguities of modernist nationalism: architectural culture and nation-building in early Republican Turkey [PDF]

open access: yes, 2004
Reviews the book "Modernism and Nation Building: Turkish Architectural Culture in the Early Republic," by Sibel ...
Akman, Ayhan
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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