Results 51 to 60 of about 13,395,687 (337)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Acculturation of Chinese and Islamic Culture at the Interior of the Ronghe Mosque [PDF]

, 2019
The architectural form of the Ronghe mosque is an architectural work with cultural tolerance related to building function change and cultural fusion. The combination of culture is manifested in the form of the mosque’s interior with various elements and ...
Andrianawati, A. (Aida ), Lestari, N. L. (Neng )   +1 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Architectural Design Optimisation in Reticulated Free-Form Canopies

Buildings, 2022
The search for the structural form of reticulated roofs is significant in interdisciplinary Architectural Design optimisation. Combining parametric design with structural logic influences the visual perception of the shape by choosing the most suitable ...
Anna Stefańska, Wiesław Rokicki
doaj   +1 more source

Forms of ritual, forms of architecture

Festival dell'Architettura Magazine, 2022
The aim of this issue is to solicit the exploration of the meaning - by scholars and researchers from Italian or foreign universities engaged in their research in an unstructured condition - of the relationships between the condition of the transition from life to death and the forms of architecture.
Renato Capozzi, Claudia Pirina
openaire   +1 more source

SPATIALGENESIS:Event based digital space making [PDF]

, 2009
: Digital technologies and processes have been used to generate architectural form for over two decades, now the recent advances in digital technologies have allowed virtual digital environments to be constructed from physical movement.
Crotch, J., Horner, Martyn, Mantho, Robert   +2 more
core  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

THE INVESTIGATION OF EXTERNAL AERODYNAMICS OFBUILDING OF UNUSUAL ARCHITECTURAL FORM

, 2018
The issues of buildings aerodynamics have always been considered rather important, and in some cases, crucial for the design of natural ventilation of buildings and smoke extraction systems. The applicable guidelines contain recommendations for regarding
V. Zhelykh, Yuriy Yurkevych, O. Savchenko   +2 more
semanticscholar   +1 more source