Results 81 to 90 of about 13,395,687 (337)
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Pattern-based software architecture for service-oriented software systems [PDF]
Service-oriented architecture is a recent conceptual framework for service-oriented software platforms. Architectures are of great importance for the evolution of software systems.
Barrett, Ronan, Pahl, Claus
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The Vienna School of Art History and (Viennese) Modern Architecture [PDF]
The essay investigates the way Strzygowski, Dvořák and Tietze interpreted contemporary architecture, and also traces the basic premises of the Vienna School in their views.
Jindřich Vybíral
doaj
Sequential Form Formation Diagrams in Architectural Design
This article discusses approaches to architectural design and the use of diagrams as a design tool, including specifications for the development process and methods of use of diagrams, and evaluates this approach that is both flexible and subjective ...
Berk Özdemir, Feride Önal
doaj +1 more source
Symbiots: Conceptual interventions into energy systems [PDF]
Symbiots set out to examine values such as ease-of-use, comfort, and rationality assumed within conventions of ‘good design’, in order to expose issues related to energy consumption and current human- (versus eco-) centered design paradigms. Exploring re-
Bergström, J. +3 more
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
THE SHAPING AND ENERGY EFFICIENCY IN THE ARCHITECTURE OF LOW DWELLING
The architectural form, its theoretical judgment and historical change, have to be based on conditions of its emergence, the reasons and purposes of the creation, the level of development of society and science, construction technologies and engineering ...
E. L. Budarin
doaj
National and Private Ambitions in the Patronage of French Cardinals at the Papal Court (Fifteenth to Sixteenth centuries) [PDF]
Few French cardinals left important traces in the form of architectural patronage in Rome during the fifteenth and sixteenth centuries, a period characterised by the alternation of times of strong tension between the French kings and the Papacy, and ...
Bardati, Flaminia
core +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source

