Results 121 to 130 of about 8,415,461 (296)
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
The “polite vernacular” in modernist rural landscapes and its challenges to architectural history
, 2017 Throughout the 20th century, many modernist architects have sought inspiration in vernacular architecture, in an attempt to address the tensions between the local and international dimensions of their activity within a world undergoing rapid change, yet ...
Fisher, Axel, Capresi, Vittoria
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Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
"A Home": Östberg’s search for the total artwork
, 2014 This paper aims to be a discovering voyage on how the Swedish architect Ragnar Östberg (1866-1945) turned the intuitions expressed in his 15-pages pamphlet entitled Ett hem. Dess byggnad och inredning (“A Home.
MONTERUMISI, CHIARA
core +1 more source
Kathleen James-Chakraborty, Architecture Since 1400
ABE Journal, 2016 Murray Fraser
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
UA Little Rock Center for Arkansas History and Culture Architectural Drawings, 1841-1979
This collection contains architectural drawings collected by the UA Little Rock Center for Arkansas History and Culture. It includes drawings of apartments and residences, cemetery structures, churches and temples, commercial buildings, government ...
Sanders & Ginocchio Architects; Trapp, Clippard & Phelps Architects; Sanders, Theodore M., 1879-1947
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Generative AI and the History of Architecture
chapter to appear in Decoding Cultural Heritage with ...
Joern Ploennigs, Markus Berger
openaire +3 more sources
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
News: How to Narrate the History of Architecture?
, 2018 Paolo Scrivano, Scientific Coordinator (with Hélène Jannière) of Mapping Architectural Criticism, delivered a keynote speech at the conference How to narrate the history of architecture? Centenary of Birth of Architectural Historian Bruno Zevi (1918-2000)
Mapping Architectural Criticism
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