Results 111 to 120 of about 17,548 (317)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
LOW COST TECHNIQUES FOR THE DIGITAL SURVEY OF A MINOAN ARCHITECTURE IN THE ARCHEOLOGICAL SITE OF PHAISTOS (CRETE) [PDF]
, 2019 D. Aiello +5 more
openalex +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
BuildingsThe future of architectural environments in China will serve the needs of, and thus be shaped/re-shaped by, the Chinese Y and Z generations. Although Shan-Shui designs have long been a classic style of architectural environment in China, there is a lack ...
Shaochen Wang, Yang Song
doaj +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Disegnare con, 2015 muraria di un’architettura complessa, generata dalletrasformazioni avvenute nel corso della sua storia, risultauno strumento essenziale per un restauro consapevole.Un’approfondita documentazione sulla struttura inseritanel suo contesto e il rilievo ...
Gaia Lisa Tacchi
doaj
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Survey on Energy - Efficient Methodologies and Architectures of Network-on-Chip
, 2016 S. Beulah Hemalatha +2 more
openalex +2 more sources
Efficient Evaluation Methods for Neural Architecture Search: A Survey [PDF]
, 2023 Xiangning Xie +6 more
openalex +1 more source