Results 141 to 150 of about 4,791,717 (318)
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
, 1914 Manuscript plane table survey map of Meredith, Geelong and Portarlington regions, Victoria. Relief shown by contours and spot heights.; Title supplied by cataloguer.; Surveyed by E.F.
Australia. Army. Survey Corps.
core
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Ordnance Survey of England and Wales [cartographic material].
, 1906 3rd ed. Topographic map series of England and Wales with relief shown by contours, spot heights and hill shading.; Sheets 1, 3 and 5 contained no coverage of Scotland until new editions of 1917, which were titled "Ordnance Survey of England and Scotland".
Great Britain. Ordnance Survey.
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Jamaica 1:50,000 (metric edition) [cartographic material] /
, 1982 Ed. 1-JSD/OSD. Topographic map series of Jamaica showing roads, tracks, built-up areas, towns, villages, railways, power transmission lines, boundaries, trigonometrical stations, woodlands, trees, plantations, pastures, water features, rice fields ...
Jamaica. Survey Department
core
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
[Topographical survey of Mesopotamia] [cartographic material] /
, 1917 Topographical survey series covering lower Mesopotamia (modern Iran and Iraq) in the vicinity of Basra, conducted 1915 - 1917, with notes on water quality and terrain conditions for travel purposes. Relief shown by contours and spot heights.; F.N. Pirrie,
Basrah Survey Party
core
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Disegnare con, 2015 The reading of the signs which define the wall stratification of a complex architecture, generated by the transformations occurred in the course of its history, is an essential instrument for an aware restoration.
Gaia Lisa Tacchi
doaj