Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Time-Aware and Power-Law Retention Gating Mechanisms in LSTMs for Irregularly Sampled Sensor Data: A Survey. [PDF]
Das D +4 more
europepmc +1 more source
Geological survey of Great Britain (England and Wales) [cartographic material] : solid and drift /
Subtitle varies: Solid geology and solid and drift geology, drift geology, solid and drift geology, solid with drift geology, solid and drift, solid.; Relief shown by contours, hachures, and spot heights. Depths shown by contours.; Title varies: 1:50,000
Great Britain. Ordnance Survey.
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GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Geological Survey of Victoria. No. 2 [cartographic material]
Caption title.; Quarter sheet 2SW is a geological map centering on the town of Broadmeadows in the parish of Will Will Rook in the county of Bourke and showing some cadastral detail. Also includes part of the parish of Tullamarine. Quarter sheet 2NW is a
Geological Survey of Victoria.
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Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
(En)Abling Architectural Research: Co-Designing With People With Intellectual Disabilities. [PDF]
Kasem M +3 more
europepmc +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Designing the syllabus for the EAP course "Architectural Art English": A needs and genre analysis-based approach. [PDF]
Sun R, Chen Z.
europepmc +1 more source
Geological survey of Great Britain (Scotland) [cartographic material] /
Various eds. Geological series of Scotland showing metamorphic rocks of uncertain age, sediments, marine and fresh water alluvia and strata poliation. Relief shown by contours and spot heights.
Great Britain. Ordnance Survey.
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