Results 51 to 60 of about 17,548 (317)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Structural Behaviour and Strength Evaluation of a Venetian Church through Finite-Element Analysis
BuildingsThe evaluation of the structural behaviour of a masonry Venetian church with a pointed barrel vault is presented in this paper through an analysis following the necessary steps of a monument study. With a detailed geometric model and material estimation,
Maria E. Stavroulaki +2 more
doaj +1 more source
A Survey on 5G and LPWAN-IoT for Improved Smart Cities and Remote Area Applications: From the Aspect of Architecture and Security [PDF]
, 2022 Emmanuel U. Ogbodo +2 more
openalex +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Cluster and characteristic analysis of Shanghai metro stations based on metro card and land-use data
Geo-spatial Information Science, 2020 Metro is an important form of public transport in Shanghai. Based on the metro card data, we conduct the cluster analysis of Shanghai metro stations according to the pattern of passenger flow changing with time.
Ping Shen +4 more
doaj +1 more source
The “Pieve di Santa Maria” in Arezzo (Italy). From the Laser Scanner Survey to the Knowledge of the Architectural Structure [PDF]
, 2021 Pietro Matracchi +3 more
openalex +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Energies, 2018 Integrated investigations have revealed abundant resources of gas hydrates on the northern slope of the South China Sea (SCS). Regarding the gas hydrate research of northern SCS, the gas hydrate related environment problem such as seabed landslides were ...
Xuemin Wu +6 more
doaj +1 more source