Results 51 to 60 of about 340,000 (305)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Field Characterization of Dynamic Response of Geocell-Reinforced Aeolian Sand Subgrade under Live Traffic

open access: yesApplied Sciences, 2023
In desert regions, aeolian sand is abundant, but it is not suitable to be used directly as the upper roadbed filler for highways. Generally, gravelly soil is mined around the desert as upper roadbed fill, resulting in high engineering expenses for road ...
Bin Gao   +5 more
doaj   +1 more source

Dynamic urban projection mapping [PDF]

open access: yes, 2017
“Dynamic projection mapping” is a variation of the best-known “projection mapping”. It considers the perceptual analysis of the urban landscape in which the video projection and the observer’s displacement speed are hypothesized.
Empler, Tommaso
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Multitask Learning Deep Neural Networks to Combine Revealed and Stated Preference Data

open access: yes, 2019
It is an enduring question how to combine revealed preference (RP) and stated preference (SP) data to analyze travel behavior. This study presents a framework of multitask learning deep neural networks (MTLDNNs) for this question, and demonstrates that ...
Wang, Qingyi   +2 more
core   +1 more source

Architecture, colour and images. Ideas and designs by Friedensreich Hundertwasser [PDF]

open access: yes, 2017
Colour, imagination, inspiration, amazement. These four words very fittingly describe the work of the Viennese artist/architect Friedrich Stowasser, better known as Hundertwasser (meaning hundred water), a master of organic thinking who between 1928 and ...
Chiavoni, Emanuela
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Application Of Project Management Principles In The Public Sector's Architectural Design Practice [PDF]

open access: yes, 2002
The implementation of MS-ISO 9000 Standards in Public Works Department of Malaysia, had an impact on the future direction of the project management phenomenon in the architectural design practice.
Sandanasamy, Reymund
core  

A survey of patterns for Service-Oriented Architectures [PDF]

open access: yesInternational Journal of Internet Protocol Technology, 2006
Service-Oriented Architectures (SOA) are a promising means to integrate heterogeneous systems, but virtually no technology-neutral approach to holistically understand SOAs exists. We tackle this problem by introducing a survey of technology-independent patterns that are relevant for SOAs, and are working towards a formalised pattern-based reference ...
Uwe Zdun   +2 more
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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