Results 51 to 60 of about 4,791,717 (318)

A generic formalism for the semantic modeling and representation of architectural elements [PDF]

open access: yes, 2007
This article presents a methodological approach to the semantic description of architectural elements based both on theoretical reflections and research experiences.
Livio De Luca   +5 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural Behaviour and Strength Evaluation of a Venetian Church through Finite-Element Analysis

open access: yesBuildings
The evaluation of the structural behaviour of a masonry Venetian church with a pointed barrel vault is presented in this paper through an analysis following the necessary steps of a monument study. With a detailed geometric model and material estimation,
Maria E. Stavroulaki   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Actors and Vehicles of Architectural Criticism (2)

open access: yes, 2016
The Role of Architectural Journals between Medium and the Message Jasna Galjer University of Zagreb The paper explores the case studies of the professional journals in the context of promoting new architectural language and their multilayered roles; from
Mapping Architectural Criticism
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Reading the Void: A Reconstructive Hypothesis for a Service Staircase at the Infantado Palace in Guadalajara Using TLS

open access: yesRemote Sensing
This study examines the relevance of Terrestrial Laser Scanning (TLS) for documenting and reconstructing architectural heritage elements that have partially or completely disappeared over time, using the remains of the service staircase of the Infantado ...
Jorge Luis López Viejo   +2 more
doaj   +1 more source

Fog Computing: A Comprehensive Architectural Survey

open access: yesIEEE Access, 2020
Fog computing is an emerging technology to address computing and networking bottlenecks in large scale deployment of IoT applications. It is a promising complementary computing paradigm to cloud computing where computational, networking, storage and ...
Pooyan Habibi   +4 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

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