Results 81 to 90 of about 17,548 (317)

K-means Clustering and Control Analysis of Main Tunneling Parameters of Mud-Water Balanced Shields in Water-Rich Round Gravel Strata

Zhongwai Gonglu
It is important to set reasonable tunneling parameters according to the ground conditions to reduce the deformation of existing tunnels, since the close crossing of new shield tunnels is likely to cause deformation in the adjacent existing tunnels. The K-
LYU Yiye, PEI Lihua, LIN Dong, YANG Xingyu, GUI Yue   +4 more
doaj   +1 more source

Experiences in Photogrammetric and Laser Scanner Surveing of Architectural Heritage

Geoinformatics FCE CTU, 2011
The integration of different methodologies and simplification of procedures is surely one of the most important current themes in survey techniques for researching cultural heritage, especially for architectural heritage.  The traditional methods for the
Mauro Caprioli, Maurizio Minchilli, Alfredo Scognamiglio   +2 more
doaj   +1 more source

Integrated cognitive architectures: a survey

Artificial Intelligence Review, 2007
This article aims to present an account of the state of the art research in the field of integrated cognitive architectures by providing a review of six cognitive architectures, namely Soar, ACT-R, ICARUS, BDI, the subsumption architecture and CLARION.
CHONG, Hui-Qing, TAN, Ah-hwee, NG, Gee-Wah   +2 more
openaire   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Associative Processor Architecture—a Survey [PDF]

ACM Computing Surveys, 1977
Yau, S. S., Fung, H. S.
openaire   +2 more sources

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Survey on Transaction Verification Model based on Blockchain Architecture

, 2021
Waqas Saeed, Husain Majid, Hafiz Mudassar Khan, Ali Akbar, Sajid Rehman Babar, I Rubasinghe, T De, J Yli-Huumo, D Ko, S Choi, S Park, K Smolander, J Yli-Huumo, D Ko, S Choi, S Park, K Smolander, M Mainelli, M Smith, J Bonneau, A Miller, J Clark, A Narayanan, J Kroll, E Felten, M Taylor, F Tschorsch, B Scheuermann, L Sankar, M Sindhu, M Sethumadhavan, I.-C Lin, T.-C Liao, E Hofmann, U Strewe, N Bosia, J Garay, A Kiayias, N Leonardos, K Christidis, M Devetsikiotis, N Abdullah, A Hakansson, E Moradian, E Karafiloski, A Mishev, Z Chen, Y Zhu, T Aste, P Tasca, T Di Matteo, L.-N Lundbaek, A D'iddio, M Huth, A Kosba, A Miller, E Shi, Z Wen, C Papamanthou, A Dubovitskaya, Z Xu, S Ryu, M Schumacher, F Wang, J Mattila, T Seppl, J Holmstrm, R Zhang, B Preneel, A Chepurnoy, T Duong, L Fan, H.-S Zhou, R Gennaro, S Goldfeder, A Narayanan, X Li, P Jiang, T Chen, X Luo, Q Wen   +80 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Factors Affecting Architectural Decision-Making Process and Challenges in Software Projects: A Survey with Architecture Experts and Practitioners

, 2022
Merve Özdeş, Oumout Chouseinoglou, Ayça Kolukısa Tarhan   +2 more
openalex   +1 more source