Results 71 to 80 of about 205,019 (293)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
American Journal of Islam and Society, 2014 When the term Ottoman architecture is used, the immediate image that comes to mind is that of the multitudes of mosque and religious buildings in Turkey and the Ottoman Empire.
Tammy Gaber
doaj +1 more source
Walley School Community Arts Center Feasibility Study [PDF]
, 2011 The Walley School community arts center initiative began in the fall of 2011 as a joint project between the Town of Bristol and Roger Williams University’s School of Architecture.
Bob Miklos,Kelly Ard, Scott Slarsky, +2 more
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Copyright issues on the protection of architectural works and designs [PDF]
Architects and engineers depend on copyright law to protect their original works. Copyright protection is automatic once a tangible medium of expression in any form of an innovative material, conforming the Copyright Designs and Patents Act 1988, is ...
Denoncourt, J, Mann, Phebe
core
Supporting reinterpretation in computer-aided conceptual design [PDF]
, 2008 This paper presents research that aims to inform the development of computational tools that better support design exploration and idea transformation - key objectives in conceptual design.
AHRC (Funder) +7 more
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
A Research on Limitations of Flexibility in Iranian Contemporary Housing [PDF]
مسکن و محیط روستا, 2015 “Flexibility” is generally defined as the ability to change in materials. In architecture and environmental designing, particularly in designing residential places that forms the main subject in this study, the term refers to spatial flexibility in man ...
akram hosseini, sommaye sharifzadeh
doaj
In Situ, 2017 The old spa building at Aix-les-Bains (Savoie) is composed of a series of constructions progressively added to the original monument, built in 1786 close to springs that were known to the Romans. The most recent significant additions date from the 1970s.
Juliette Rolland
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source