Results 111 to 120 of about 127,846 (271)

Implementing the "SMART" Framework for Effective Management of Inactive Archives: A Case Study of the Faculty of Economics, Universitas Negeri Semarang

Soshum: Jurnal Sosial dan Humaniora
Effective archive management is essential for organizations, companies, and agencies to support administrative processes, decision-making, and policy development.
Rohmawati, Ahmad Saeroji, Maya Sari, Moch Faizal Rachmadi   +3 more
doaj   +1 more source

ARCHIVES CLASSIFICATION PLANS : comparative study of Brazilian, Spain and Portugal Classification Plans

, 2017
This comparative study of Classification Plans in Brazilian, Spain and Portugal archives. This is a documentary research, being characterized as descriptive and bibliographical. The instrument for collecting information was an ANEEL document containing the Classification Plan of the body and also documents of the Local Administration of Portugal and ...
Lopes, Thiago Roberto, Blattmann, Ursula
openaire   +1 more source

METTL5 Enables Immune Evasion of Liver Cancer via Chemokine mRNA Translation Regulation

Advanced Science, EarlyView.
METTL5 reshapes the tumor immune microenvironment through ribosome 18S rRNA m6A modification to regulate the translation of chemokine mRNA. Targeting METTL5‐mediated immunosuppression unleashes anti‐tumor immunity and improves the efficacy of anti‐PD‐1 therapy.
Shuang Li, Xiao Zhao, Tongtong Song, Qiaoyi Chen, Yanqing Wu, Yuting Zhang, Jingying Chen, Yifan Wu, Bin Li, Xinyue Zhang, Zihao Dai, Lixia Xu, Yubin Xie, Alfred Sze‐Lok Cheng, Jianping Guo, Ming Kuang, Shuibin Lin, Zhenwei Peng, Sui Peng, Xuezhen Zeng   +19 more
wiley   +1 more source

Modulating Purothionin Accumulation and Signal Peptide Cleavage Fine‐Tunes Wheat Flour Gluten Properties to Improve Cookie‐Making Quality

Advanced Science, EarlyView.
Dual genetic strategies for improving wheat processing quality by regulating purothionin accumulation to modulate gluten quantity and quality. The first strategy involves targeting signal peptide (SP) cleavage sites (e.g., through mutation) to indirectly reduce gluten content, thereby disrupting gluten network formation.
Yijie Liu, Siyuan Chang, Zhaoheng Zhang, Tianqi Kang, Mingde Liu, Yuan Zong, Fei Ni, Yinguang Bao, Ruijie Zhang, Xiaobang Zhang, Jinkun Du, Mingming Xin, Zhaorong Hu, Jie Liu, Zhongfu Ni, Qixin Sun, Yingyin Yao   +16 more
wiley   +1 more source

The Filing plan. Legal, Technical, and Practical Issues

JLIS.it
The new Guidelines on the creation, management, and preservation of digital documents, approved by the Italian Digital Agency (AgID) and effective as of January 1, 2022, place particular emphasis not on individual records, but rather on fundamental ...
Gianni Penzo Doria
doaj   +1 more source

Privileging information is inevitable [PDF]

, 2006
Libraries, archives and museums have long collected physical materials and other artefacts. In so doing they have established formal or informal policies defining what they will (and will not) collect.
Currall, J.E.P., Moss, M., Stuart, S.A.J.   +2 more
core  

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

Classification and archival methods in the archive of administrative support coordinator CED UFSC

, 2017
Apresenta o estudo, identificação e análise dos documentos em âmbito corrente e intermediário custodiados pela Coordenadoria de Apoio Administrativo do Centro de Ciências da Educação da Universidade Federal de Santa Catarina. Desenvolve atividades práticas de estágio e realiza a descrição arquivística.
Souza, Ana Cristina, Bahia, Eliana Maria dos Santos   +1 more
openaire   +1 more source

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

Advanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi, Mohammad Mahdi Hosseini, Ahmadreza Argha, Roxana Zahedi, Nigel H. Lovell, Hamid Alinejad‐Rokny   +5 more
wiley   +1 more source