Results 161 to 170 of about 127,846 (271)

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

Employing nanopore sequencing on FFPE-derived DNA for CNS tumor diagnostics. [PDF]

Acta Neuropathol Commun
Kerbs P, Brehm M, Haag D, Bogumil H, Patel A, Sill M, Berghaus N, Göbel K, Schrimpf D, Tabatabai G, Schittenhelm J, Sakowitz O, Stadelmann C, Goldbrunner R, Etminan N, Ratliff M, Herold-Mende C, Krieg S, Wick W, Jones DTW, von Deimling A, Sahm F, Göller P.   +22 more
europepmc   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Quantification of Alzheimer disease neuropathology using tissue microarrays. [PDF]

J Neuropathol Exp Neurol
Nguyen-Hao HT, Liu J, Novelli M, Maskey D, Schwartz RS, Harari O, Sutherland GT.   +6 more
europepmc   +1 more source

Classification in Archives and Libraries: between tradition and theoretical transformation

JLIS.it, 2017
Guercio, Maria, Gnoli, Claudio
openaire   +7 more sources

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

Praktik Klasifikasi Arsip Siaran: Studi Kasus pada Stasiun Radio LPP RRI Malang, Kalimaya Bhaskara FM dan City Guide FM

Tik Ilmeu: Jurnal Ilmu Perpustakaan dan Informasi
Classification of audio archives is one of the challenges for radio stations in managing their audio to maintain the sustainability of the information they have. This study aims to adjust the implementation of broadcast archive classification at the LPP
Zsa Zsa Candraningtyas, Moh. Safii, Sokhibul Ansor   +2 more
doaj  

First report on detection and molecular characterization of alphacoronaviruses in the small Indian mongoose (Urva auropunctata). [PDF]

Virol J
Kulberg JL, Becker AAMJ, Malik YS, Ghosh S.   +3 more
europepmc   +1 more source

Smart Optogenetics for Real‐Time Automated Control of Cardiac Electrical Activity

Advanced Science, EarlyView.
We are able to stop dangerous heart‐rhythm spirals before they fully form. Within about 100 ms, it pinpoints the spiral's tiny central tip (≈0.9 mm) using light‐based sensing and machine learning, then shines targeted light to shut it down. This fast, precise, closed‐loop approach detects, targets, and terminates arrhythmias in real time.
Shanliang Deng, Niels Harlaar, Juan Zhang, Sven O. Dekker, Nina N. Kudryashova, Huiling Zhou, Cindy I. Bart, TianYi Jin, Georgy Derevyanko, Willem van Driel, Alexander V. Panfilov, René H. Poelma, Antoine A. F. de Vries, GuoQi Zhang, Tim De Coster, Daniël A. Pijnappels   +15 more
wiley   +1 more source

Deep learning finds convergent melanocytic morphology despite noisy archival slides. [PDF]

Cell Rep Methods
Tada M, Gaskins G, Ghandian S, Mew N, Keiser MJ, Keiser ES.   +5 more
europepmc   +1 more source