Results 231 to 240 of about 9,582,228 (342)

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

open access: yesAdvanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen   +7 more
wiley   +1 more source

Multi‐Tissue Omics Analysis Uncovers Translational Regulation Underlying Complex Traits in Pigs

open access: yesAdvanced Science, EarlyView.
Integrated multi‐omics across pig breeds and tissues reveals key principles of post‐transcriptional translational regulation and their contribution to trait formation. A gene network framework integrating transcriptomic and translatomic data is developed and applied to elucidate the genetic basis of meat production, offering new insights into mammalian
Chao Wang   +13 more
wiley   +1 more source

Small things matter: Lack of extraislet β cells in type 1 diabetes. [PDF]

open access: yesSci Adv
Murrall K   +14 more
europepmc   +1 more source

Life‐Cycle Assessment of Printed Electronic Components ‐ Case Study for Organic Electrochemical Transistors

open access: yesAdvanced Electronic Materials, EarlyView.
This tutorial introduces a practical framework for implementing early‐stage Life‐Cycle Assessment (LCA) in flexible and printed electronics. Using organic electrochemical transistors (OECTs) as a case study, the modular Process‐of‐Record and open‐access inventory provides a rich resource adaptable to a plethora of technologies in printed electronics ...
Laura Teuerle   +6 more
wiley   +1 more source

How Particle Size Affects Consolidation Behavior, Strain and Properties of Li6PS5Cl Fast Ionic Conductors

open access: yesAdvanced Energy Materials, EarlyView.
The densification process of Li6PS5Cl powders with varying particles size distributions reveals differences in smaller and larger distributions. Higher strain is revealed for the smaller particle size distribution from X‐ray diffraction. Discrete element method simulations uncover that the reason for the higher strain is not the particle size itself ...
Vasiliki Faka   +14 more
wiley   +1 more source

Validation of an Adapted NGS-Based Clonality Assay for MRD Monitoring in B-ALL Using Archived and Follow-Up Samples. [PDF]

open access: yesEJHaem
Suryavanshi M   +10 more
europepmc   +1 more source

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