Results 221 to 230 of about 36,168 (305)

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang   +10 more
wiley   +1 more source

Temperature Sensitivity and Adaptation of Cereal Yields: Empirical Evidence From Italy

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT This paper investigates the evolving temperature sensitivity and climate adaptation of cereal yields in Italy from 1952 to 2023, using province‐level data for maize, common wheat, and durum wheat. Employing panel data econometric methods, we estimate yield responses to heat exposure, changes in sensitivity over time, and adaptation to climate ...
Paolo Nota   +2 more
wiley   +1 more source

Factors Affecting Recollapse of the Augmented Vertebrae After Percutaneous Vertebral Augmentation: A Prospective Study

open access: yesAGING MEDICINE, EarlyView.
To investigate the relevant factors of augmented vertebrae recollapse after percutaneous vertebral augmentation (PVA) for the treatment of osteoporotic vertebral compression fractures (OVCFs). Intervertebral cleft (IVC) and those with PVP intervention are at higher risk of recollapse.
Yawen Zhang   +6 more
wiley   +1 more source

Multidisciplinary identification of human skeletal remains from the karst abyss in Demänovská Valley (19th-20th century calCE, Slovakia). [PDF]

open access: yesSci Rep
Barta P   +8 more
europepmc   +1 more source

Charting the Path to Increased Oil Palm Output in Ghana Beyond Area Expansion: Technology or Managerial Capacity — Which Leads the Way?

open access: yesAgribusiness, EarlyView.
ABSTRACT This study sets out to investigate the prospects for raising oil palm output in sub‐Saharan Africa, particularly Ghana, without further expansion of cropland. Given global concerns about oil palm's role in deforestation and land use change, the focus is on enhancing productivity on existing farmlands.
Jacob Asravor   +3 more
wiley   +1 more source

Microglia in diffuse midline glioma contribute to extracellular matrix remodelling and cancer cell invasion. [PDF]

open access: yesCell Death Dis
Keane L   +9 more
europepmc   +1 more source

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