Results 281 to 290 of about 283,865 (345)

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

Advanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen, Zening Huang, Rui Chang, Wei Gao, Yajing Qiu, Bin Sun, Chen Hua, Xiaoxi Lin   +7 more
wiley   +1 more source

Association of a CD44s-v5-v6 Null Phenotype with Advanced Stage Cholangiocarcinoma: A Preliminary Study. [PDF]

Cancers (Basel)
Myint KZ, Mongkonsiri T, Jinawath A, Tohtong R.   +3 more
europepmc   +1 more source

Multi‐Tissue Omics Analysis Uncovers Translational Regulation Underlying Complex Traits in Pigs

Advanced Science, EarlyView.
Integrated multi‐omics across pig breeds and tissues reveals key principles of post‐transcriptional translational regulation and their contribution to trait formation. A gene network framework integrating transcriptomic and translatomic data is developed and applied to elucidate the genetic basis of meat production, offering new insights into mammalian
Chao Wang, Yuanyuan Zhang, Choulin Chen, Xiaoxian Xu, Shenghua Qin, Junyan Qi, Yongzhou Bao, Huiming Li, Ruipu Chen, Weigang Zheng, Zhilong Chen, Lingzhao Fang, Yunxiang Zhao, Yuwen Liu   +13 more
wiley   +1 more source

Animal tracking with particle algorithms informs protected area design. [PDF]

Sci Adv
Lavender E, Scheidegger A, Albert C, Biber SW, Brodersen J, Aleynik D, Cole G, Dodd J, Wright PJ, Illian J, James M, Smout S, Thorburn J, Moor H.   +13 more
europepmc   +1 more source

Life‐Cycle Assessment of Printed Electronic Components ‐ Case Study for Organic Electrochemical Transistors

Advanced Electronic Materials, EarlyView.
This tutorial introduces a practical framework for implementing early‐stage Life‐Cycle Assessment (LCA) in flexible and printed electronics. Using organic electrochemical transistors (OECTs) as a case study, the modular Process‐of‐Record and open‐access inventory provides a rich resource adaptable to a plethora of technologies in printed electronics ...
Laura Teuerle, Tommy Meier, Klara Hänisch, Finn Jaekel, Yeohoon Yoon, Andreas Wendel, Hans Kleemann   +6 more
wiley   +1 more source

The stigmatization of patients with chronic pain due to assessed exaggeration of symptoms. [PDF]

Can J Pain
Clarke H, Craig K, Deamo Assis R, Mittal N, Fitzcharles MA.   +4 more
europepmc   +1 more source

How Particle Size Affects Consolidation Behavior, Strain and Properties of Li6PS5Cl Fast Ionic Conductors

Advanced Energy Materials, EarlyView.
The densification process of Li6PS5Cl powders with varying particles size distributions reveals differences in smaller and larger distributions. Higher strain is revealed for the smaller particle size distribution from X‐ray diffraction. Discrete element method simulations uncover that the reason for the higher strain is not the particle size itself ...
Vasiliki Faka, Mohammed Alabdali, Martin A. Lange, Franco M. Zanotto, Can Yildirim, Mikael Dahl Kanedal, Jędrzej Kondek, Matthias Hartmann, Oliver Maus, Dominik Daisenberger, Michael Ryan Hansen, Jozef Keckes, Daniel Rettenwander, Alejandro A. Franco, Wolfgang G. Zeier   +14 more
wiley   +1 more source

The GSA Family in 2025: A Broadened Sharing Platform for Multi-omics and Multimodal Data. [PDF]

Genomics Proteomics Bioinformatics
Zhang S, Chen X, Jin E, Wang A, Chen T, Zhang X, Zhu J, Dong L, Sun Y, Yu C, Zhou Y, Fan Z, Chen H, Zhai S, Sun Y, Chen Q, Xiao J, Song S, Zhang Z, Bao Y, Wang Y, Zhao W.   +21 more
europepmc   +1 more source