Results 41 to 50 of about 283,865 (345)
“There is a history in all men’s lives”: a journey in transnational documentation
Although archives are understood as unique and undivided records accumulated throughout an individual or a collective's existence, archivists and researchers at large can be confronted by the dissemination in various institutions or countries of ...
Marie-Alice Le Corvec
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Archival ethics: The truth of the matter [PDF]
This essay explores the question of whether records professionals are as aware of the ethical dimensions of their work as they should be. It consider first the historical and professional context of archival ethics, then examines a recent case about ...
Adkins +51 more
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
The article is an introduction to the topic of the archival science which is concentrated on practical use of archive. First part contains definitions of basic terms of archive and archival documents and informs about the system of archives in Czech ...
Jan Šimek
doaj
Sociolinguistics II: Deviance, Dystopia, And Democracy (LING82) Syllabus [PDF]
This course builds upon foundational concepts in sociolinguistic theory to examine discourses of news and entertainment media, across science fiction and politics.
Thomas, Jamie A.
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Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The archive beyond the archive
The publication of Federico Valacchi’s book, Gli archivi tra storia, uso e futuro: dentro la società (Milano, Editrice Bibliografica, 2021) it is an opportunity to reflect on the role of archives and archivists.
Mario Aldo Toscano
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The Sciences of the Archive [PDF]
Since the mid-nineteenth century, classifications of knowledge have opposed the bookish, history-conscious humanities to the empirical, amnesiac sciences. Yet in the sciences of the archive, the library stands alongside the laboratory, the observatory, and the field as an important site of research.
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