Results 111 to 120 of about 25,687,323 (301)
Historians' Experiences Using Digitized Archival Photographs as Evidence [PDF]
, 2016 Widespread digitization has presented scholars with unprecedented access to archival sources. In particular, the availability of archival photographs through online collections has been championed as an opportunity to fill in underrepresented histories ...
Chassanoff, Alexandra
core +2 more sources
Optical Manipulation of Whispering Gallery Mode Microlasers for Controlled Cellular Delivery
Advanced Optical Materials, EarlyView.Optically trapped whispering‑gallery microlasers are precisely positioned onto non‐phagocytic mammalian cells to report local refractive‑index changes in real time. Time‑dependent wavelength shifts reveal successive stages from membrane contact to internalization.
Soraya Caixeiro +3 more
wiley +1 more source
Advanced Science, EarlyView.Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai +15 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao +11 more
wiley +1 more source
Advanced Science, EarlyView.A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang +19 more
wiley +1 more source
Review Essay: Archivists and the Use of Archival Records; Or a View from the World of Documentary Editing [PDF]
, 1991 The past decade has been a time of new calls for reassessment of the archival reference function and analysis of the use of archival and historical records.
Cox, Richard J.
core +1 more source
Archival fiction: Archival poetics in American multimodal literature [PDF]
This thesis demonstrates how archival poetics permeates contemporary American multimodal literature thematically, visually, and structurally. Whilst recent scholars have noted the archive’s influence on contemporary literature, my project extends this ...
Ivansson, Elin Anny Caroline
core +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
A Perspective on Interactive Theorem Provers in Physics
Advanced Science, EarlyView.Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley +1 more source