Results 31 to 40 of about 257,402 (243)
Digital preservation of scholarly content, focusing on the example of the CLOCKSS Archive
In this article the author explores the development of digital preservation, including consideration of what it is and what it is not, and looks at the challenges that preservation of multiple formats of digital scholarship brings.
Randy S Kiefer
doaj +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Economic and Educational Policies of the Anglo-Iranian Oil Company and the Experience of Apprenticeship in the Oil Industry during the Interwar Years (1921–1945) [PDF]
This study examines the educational policies of the Anglo-Iranian Oil Company during the interwar period (1921–1945). In these years, the growing need for skilled labor in the nascent oil industry, combined with pressure from the Iranian government to ...
Robabe Motaghedi +1 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
CoreTrustSeal: From academic collaboration to sustainable services
National and international digital repositories must design and deliver sustainable services as a foundation for a range of scientific and data management infrastructures while reducing costs and avoiding duplication of effort.
Hervé L'Hours +2 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Fortunoff Video Archive: New Initiatives for a New Digital Archive
The Fortunoff Archive recently completed a number of important milestones including the digitization of its entire collection, the development of a digital access system, migration of legacy metadata, and the launch of a partner site program that ...
Kevin Glick, Stephen Naron
doaj +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Southern Scandinavia is Europe’s richest region in terms of figurative rock art. It is imperative to document this cultural heritage for future generations.
Horn Christian +3 more
doaj +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source

