Results 31 to 40 of about 7,394,353 (302)

Ante-Autobiography and the Archive of Childhood [PDF]

open access: yes, 2013
This essay examines the concept of children’s autobiography via several autobiographical extracts written by the author as a child. Although only a small proportion of people will compose and publish a full-length autobiography, almost everyone will ...
Lynch, C
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Revisiting Qualitative Data Reuse

open access: yesSAGE Open, 2017
Secondary analysis of qualitative data entails reusing data created from previous research projects for new purposes. Reuse provides an opportunity to study the raw materials of past research projects to gain methodological and substantive insights.
Libby Bishop, Arja Kuula-Luumi
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Research Project for the Preservation of the Cultural and Historical Heritage

open access: yesDigital Presentation and Preservation of Cultural and Scientific Heritage, 2017
The exceptional contribution of Felix Kanitz to Bulgarian scientific and cultural development is an occasion to present to Bulgarian and European public his artistic and documentary heritage, to turn again our attention to the personality and the ...
Darina Ilieva, Gabriela Vaptzarova
doaj   +1 more source

The Archive of Unrealised Devices

open access: yes, 2014
Google Patents is an eight-year-old virtual searchable database containing the United States Patent and Trademark Office (USPTO) and the European Patent Office (EPO) patents, with US patent applications dating back to 1790. This searchable online archive
Stansbie, Lisa
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Digital preservation of scholarly content, focusing on the example of the CLOCKSS Archive

open access: yesInsights: The UKSG Journal, 2015
In this article the author explores the development of digital preservation, including consideration of what it is and what it is not, and looks at the challenges that preservation of multiple formats of digital scholarship brings.
Randy S Kiefer
doaj   +1 more source

Home - About - Disclaimer - Privacy