Results 31 to 40 of about 276,047 (250)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Digital preservation of scholarly content, focusing on the example of the CLOCKSS Archive

open access: yesInsights: The UKSG Journal, 2015
In this article the author explores the development of digital preservation, including consideration of what it is and what it is not, and looks at the challenges that preservation of multiple formats of digital scholarship brings.
Randy S Kiefer
doaj   +1 more source

Tragedy of Errors at Warp Speed: The 2019 Unrest

open access: yesGlobal Storytelling, 2021
The 2019 unrest in Hong Kong was the result of complex factors simmering over the years, culminating in a tragedy of errors unreeling at warp speed.
Sam Ho
doaj   +2 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

A study on digital literacy and influencing factors among Chinese seafarers

open access: yesScientific Reports
Digital literacy and skills have become critical indicators of international competitiveness, gaining attention across all sectors. As digital transformation accelerates, the shipping industry, a pivotal center of global trade, faces new challenges.
Junhua Li   +4 more
doaj   +1 more source

CoreTrustSeal: From academic collaboration to sustainable services

open access: yesIASSIST Quarterly, 2019
National and international digital repositories must design and deliver sustainable services as a foundation for a range of scientific and data management infrastructures while reducing costs and avoiding duplication of effort.
Hervé L'Hours   +2 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

By All Means Necessary – 2.5D and 3D Recording of Surfaces in the Study of Southern Scandinavian Rock Art

open access: yesOpen Archaeology, 2018
Southern Scandinavia is Europe’s richest region in terms of figurative rock art. It is imperative to document this cultural heritage for future generations.
Horn Christian   +3 more
doaj   +1 more source

Fortunoff Video Archive: New Initiatives for a New Digital Archive

open access: yesUmanistica Digitale, 2019
The Fortunoff Archive recently completed a number of important milestones including the digitization of its entire collection, the development of a digital access system, migration of legacy metadata, and the launch of a partner site program that ...
Kevin Glick, Stephen Naron
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

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