Results 211 to 220 of about 458,612 (282)

A quality framework for cryopreserved rodent disease models: INFRAFRONTIER quality principles in EMMA archiving and distribution. [PDF]

Mamm Genome
Ehlich H, Blease A, Biju R, Gustems M, Song F, Fessele S, Massimi M, Bozonelos K, Ntafis V, Hiltunen AE, Marschall S, Stoeger C, Khorshidi Z, Ziadi A, Jambou K, Armagno A, Scavizzi F, Raspa M, Fernandez J, Del Hierro MJ, Ayadi A, Pensavalle J, Prevost G, Dufková L, Krupkova M, Nickl P, Krimpenfort P, van de Ven M, Jonkers J, Valera Vázquez G, Raess M, Beckers J, Moles A, Dahlhoff M, Montoliu L, Hérault Y, Hinttala R, Kontoyiannis DL, Sedlacek R, Hrabě de Angelis M, Boersma AA, Matteoni R.   +41 more
europepmc   +1 more source

Programmable Information Processing With Reconfigurable Self‐Contact Variable Stiffness Mechanical Metamaterial

Advanced Science, EarlyView.
Reconfigurable self‐contact variable stiffness metamaterials based on shape memory polymers enable programmable stiffness switching. Static arrays store and encrypt information with immunity to electromagnetic interference, while asymmetric stiffness converts symmetric vibration into directional matter transport.
Huadong Qin, Wenyu Zhu, Xin Wang, Cheng Shen, Li Cheng, Tian Jian Lu, Terence Xiaoteng Liu, Han Meng   +7 more
wiley   +1 more source

Prospective cohort study identifies barriers and facilitators to point-of-care ultrasound use in an academic emergency department. [PDF]

BMJ Open Qual
Platt A, Peterson T, Peethumnongsin E, Kuchibhatla M, Theophanous RG.   +4 more
europepmc   +1 more source

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

Advanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen, Zhiquan Liu, Wenmin Wang, Qing Wang, Tia J. Kowal, Fan Zhang, Grzegorz Walkiewicz, Faruk Hossen, Herbert M. Lachman, Jinqiong Zhou, Yiting Wang, Yang Sun   +11 more
wiley   +1 more source

Radiology reporting in the age of artificial intelligence: implications for patient safety. [PDF]

BMJ Qual Saf
Toker I, Jansen S, Knoche J, Lorenz D.
europepmc   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

A practical guide to the implementation of AI in orthopaedic research-Part 4: Prerequisites for a successful orthopedics AI-driven project in terms of interdisciplinary collaboration, data management, ethical approval and technology. [PDF]

J Exp Orthop
Longo UG, Merone M, Schena E, Bandini B, Nicodemi G, Zsidai B, Hilkert AS, Senorski EH, Grassi A, Ley C, Herbst E, Hirschmann MT, Kopf S, Seil R, Tischer T, Feldt R, Samuelsson K, Oettl FC.   +17 more
europepmc   +1 more source

Molecular Atlas of Key Food Odorants Reveals Mixture‐Level Organization and Enables Generative Aroma Design

Advanced Science, EarlyView.
KFO‐Atlas reveals how real‐world aromas are organized as structured mixtures rather than individual molecules. Building on these principles, KFO‐Gen, a generative AI framework, designs perceptually valid aroma formulations and reconstructs meat‐like aromas exclusively from plant‐derived odorants, providing a foundation for mixture‐level studies and AI ...
Jingzhi Zhang, Huadong Xing, Antonella Di Pizio, Qinfei Ke, Xingran Kou, Dachuan Zhang   +5 more
wiley   +1 more source

Correction: The effect of IGF-1 on cartilage injury in bone marrow mesenchymal stem cells through the BMP2-Smad1/5 signaling pathway. [PDF]

In Vitro Cell Dev Biol Anim
Ye H, Shao L.
europepmc   +1 more source