Results 291 to 300 of about 376,123 (355)

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Precision nutrition across climates: decoding diet, tradition, and genomic adaptations from South Asia to the Arctic. [PDF]

Front Nutr
Pathak AK, Kolesnikova A, Sambreker DU, Org E, Kivisild T.   +4 more
europepmc   +1 more source

Oligohistidine‐Functionalized Single‐Walled Carbon Nanotube‐Guided RNA Delivery to Improve Shoot Regeneration Efficiency in Plant Calli

Advanced Functional Materials, EarlyView.
The pH‐sensitive His6‐SWNTs, which is functionalized with oligohistidine, can deliver STTM396 molecules into callus cells. The STTM396–SWNT complex treatments enhance shoot regeneration efficiency by regulating the miR396‐GRF module in Arabidopsis and tomato calli.
Yeong Yeop Jeong, Hyuna Kwak, Woojin Jeong, Hongwoo Lee, Su‐Ji Jeon, Hyo‐Jun Lee, Pil Joon Seo, Seon‐Yeong Kwak   +7 more
wiley   +1 more source

Atlantification drives recent strengthening of the Arctic overturning circulation. [PDF]

Sci Adv
Årthun M, Brakstad A, Dörr J, Johnson HL, Mans C, Semper S, Våge K.   +6 more
europepmc   +1 more source

Electrochemically Driven Tandem In‐Plane Reduction and FeCl3‐ Intercalation of Highly Crystalline Graphene Oxide Thin Films

Advanced Functional Materials, EarlyView.
This study presents a green processing route for high‐performance reduced graphene oxide (rGO) transparent conductive films (TCFs) using highly crystalline Brodie's GO. In‐plane electrochemical reduction forms rGO on insulating substrates without toxic reductants or heat. Subsequent FeCl₃ intercalation enhances conductivity, overcoming the transparency–
Tatsuki Tsugawa, Kazuto Hatakeyama, Junya Kawasaki, Agamoni Pathak, Kazuhito Tsukagoshi, Shintaro Ida, Takaaki Taniguchi   +6 more
wiley   +1 more source

Assessing vulnerability of Arctic fish species to climate change. [PDF]

Discov Ocean
Sora KJ, Wabnitz CCC, Steiner NS, Sumaila UR, Hoover C, Niemi A, Loseto L, Lea EV, Breiter CC, Palacios-Abrantes J, Reygondeau G, Farnole P, Sou T, Cheung WWL.   +13 more
europepmc   +1 more source

Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions

Advanced Functional Materials, EarlyView.
An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park, Dong‐yup Lee, Sungsoo Lim, JangHyuk Kim, Min‐Gyu Lee, Chang Seo Park, Hyeonuk Na, Yong Eun Cho, Yun Hyeok Lee, Junsang Doh, Jeong‐Yun Sun   +10 more
wiley   +1 more source

Svalbard winter warming is reaching melting point. [PDF]

Nat Commun
Bradley JA, Molares Moncayo L, Gallo G, Brusca J, Viglezio T, Pasotti J, Giovannelli D.   +6 more
europepmc   +1 more source

Glutathione and Laccase Dual‐Responsive Lignin Nanocarriers Inspired by Host‐Pathogen Interactions for Fungicide Delivery

Advanced Functional Materials, EarlyView.
Discover bio‐inspired fungicide‐loaded lignin nanocarriers that mimic host‐pathogen interactions, unleashing targeted fungicide release in response to glutathione and laccase. These innovative biobased nanocarriers promise superior crop protection, with increased photostability, enhanced foliar retention, and enabling bidirectional translocation for a ...
Wenlong Liang, Jingli Cheng, Lianmeng Liu, Jinhao Zhao, Frederik R. Wurm   +4 more
wiley   +1 more source

Whole Genome Sequencing Reveals How Plasticity and Genetic Differentiation Underlie Sympatric Morphs of Arctic Charr. [PDF]

Mol Ecol
Kurta K, Fedi MO, Baker K, Barker T, Catchpole L, Ciofi C, Cocco A, Collins J, Diedericks G, Diroma MA, Durrant A, Hindar K, Iannucci A, Irish N, Knitlhoffer V, Laikre L, Leitão HG, Lucchini S, McTaggart S, Pálsson A, Pettersson ME, Ryman N, Snorrason SS, Svardal H, Swarbreck D, Waterhouse RM, Watkins C, Wood JMD, Xiao H, Gharbi K, Jónsson ZO, Andersson L.   +31 more
europepmc   +1 more source