Results 301 to 310 of about 800,031 (390)

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

Advanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong, Shumin Xie, Ruohao Fan, Fengjun Wang, Junyi Zhang, Zhihai Xie, Yongzhen Mo, Hua Zhang, Weihong Jiang   +17 more
wiley   +1 more source

Between light and dark, source and sink: N₂O dynamics in a subarctic, nutrient-poor permafrost peatland

Triches N, Bolek A, Rovamo M, Lamprecht R, Hashmi W, Yazbeck T, Ivanova K, Eves N, Paul D, Virkkala A, Vesala T, Biasi C, Marushchak M, Goeckede M.   +13 more
europepmc   +1 more source

Effects of crude oil and high salinity on eggs and early naupliar stages of the copepod <i>Calanus hyperboreus</i>. [PDF]

J Plankton Res
Ntinou IV, Rist S, Rask S, Lindegren M, Nielsen TG, Varpe Ø.   +5 more
europepmc   +1 more source

Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation

Advanced Science, EarlyView.
Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong, Aima Huang, Ziqing Zhao, Bikai Lai, Xin Pan, Huiyu Yang, Xiaohan Xu, Tianwei Wang, Fangchen Zhao, Zhimin Zhang, Yongbo Xue, Guanjun Deng, Wenbin Deng, Jianwei Chen   +13 more
wiley   +1 more source

Space Use of an Expanding Generalist Predator Is Shaped by Human, Marine and Seasonal Effects on Arctic Tundra. [PDF]

Ecol Evol
Hofhuis SP, Tarroux A, Ims RA, Ehrich D.
europepmc   +1 more source

Environmental Decision-Making in the Arctic Council: What is the Role of Indigenous Peoples?

, 2015
Michaela Louise Coote
openalex   +1 more source

Borealisation of Plant Communities in the Arctic Is Driven by Boreal-Tundra Species. [PDF]

Ecol Lett
García Criado M, Barrio IC, Speed JDM, Bjorkman AD, Elmendorf SC, Myers-Smith IH, Aerts R, Alatalo JM, Betway-May KR, Björk RG, Björkman MP, Blok D, Cooper EJ, Cornelissen JHC, Gould WA, Gya R, Henry GHR, Hermanutz L, Hollister RD, Jägerbrand AK, Jónsdóttir IS, Kaarlejärvi E, Khitun O, Lang SI, Macek P, May JL, Michelsen A, Normand S, Olsen SL, Post E, Rinnan R, Schmidt NM, Sjogersten S, Tolvanen A, Töpper JP, Trant A, Vandvik V, Vowles T.   +37 more
europepmc   +1 more source

Alaska’s Native History [PDF]

, 2014
Hensley, William L. Iggiagruk
core   +1 more source

Shallow coastal zones are key mediators in Arctic land-ocean carbon fluxes. [PDF]

Commun Earth Environ
van Crimpen FCJ, Madaj L, van Genuchten JM, Tesi T, Whalen D, Scharffenberg K, Bröder L, Fritz M, Vonk JE.   +8 more
europepmc   +1 more source

Robotic assisted radical prostatectomy improves biochemical recurrence-free survival: The PROCA-life study. [PDF]

J Robot Surg
Knutsen T, Aarsaether E, Wilsgaard T, Støyten M, Stikbakke E, Richardsen E, Larsen M, Thune I, Haugnes HS.   +8 more
europepmc   +1 more source