Results 141 to 150 of about 2,287,088 (335)

First in vivo evaluation of a potential SPECT brain radiotracer for the gonadotropin releasing hormone receptor

open access: yesBMC Research Notes, 2018
Objectives In vivo evaluations of a gonadotropin releasing hormone-receptor single photon emission computed tomography radiotracer for non-invasive detection of gonadotropin releasing homone-receptors in brain.
Richard Fjellaksel   +7 more
doaj   +1 more source

Identification and Comparison of Gray Literature in Two Polar Libraries: Australian Antarctic Division and Scott Polar Research Institute [PDF]

open access: yes, 2009
Gray literature collections were investigated and compared at the libraries of the Australian Antarctic Division (AAD) and the Scott Polar Research Institute (SPRI) in order to improve accessibility.
Carle, Daria O.
core  

Epidemiology, impact and control of rabies in Nepal : a systematic review [PDF]

open access: yes, 2016
Background: Rabies is a vaccine-preventable viral zoonosis belonging to the group of neglected tropical diseases. Exposure to a rabid animal may result in a fatal acute encephalitis if effective post-exposure prophylaxis is not provided.
Ale, Anita   +13 more
core   +4 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Kvik: three-tier data exploration tools for flexible analysis of genomic data in epidemiological studies [v2; ref status: indexed, http://f1000r.es/5hl]

open access: yesF1000Research, 2015
Kvik is an open-source framework that we developed for explorative analysis of functional genomics data from large epidemiological studies. Creating such studies requires a significant amount of time and resources. It is therefore usual to reuse the data
Bjørn Fjukstad   +4 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Special Issue: Food Sustainability, the Food System, and Alaskans [PDF]

open access: yes, 2011
[Geography] -- The Alaska Food Policy Council: Everyone knows that food is important, but our dependence upon Outside for the stuff of life has finally begun to seem, well, just a little discomfiting to Alaska's policymakers.
School of Natural Resources and Agricultural Sciences, Agricultural and Forestry Experiment Station, University of Alaska
core  

Environmental medicine in an Arctic perspective: "The Arctic dilemma" revisited

open access: yesInternational Journal of Circumpolar Health, 2012
When, on June 16 2006, at the 13th InternationalCongress on Circumpolar Health in Novosibirsk,I received the Hildes Award, it was withgratitude and with a humble mind. Humble,because so many others would have been justas qualified as I, and grateful, because somepeople, by nominating me, have found thatwhat I have done during my career was worththis ...
openaire   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Marine Protected Areas: Smart Investments in Ocean Health [PDF]

open access: yes, 2015
Expanding ocean protection could return an increase in jobs, resources and services that far outweigh the costs, according to an analysis of new research commissioned by WWF on marine protected areas.
Emilie Reuchlin-Hugenholtz   +1 more
core  

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