Results 171 to 180 of about 2,958,713 (246)

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source

Nanoporous Silica Embedded in Nanoporous Platinum: A Versatile Composite Coating for Implant‐Associated Drug Delivery From Neuronal Electrodes

Advanced Materials Technologies, EarlyView.
Nanoporous silica nanoparticles incorporated in nanoporous platinum offer the possibility for implant‐associated drug delivery from neuronal electrodes. ABSTRACT Sensorineural hearing loss, resulting from damage to the hair cells of the inner ear, profoundly impairs quality of life.
Mosaieb Habib, Tim‐Joshua Strauß, Jennifer Harre, Madeleine Goblet, Florian Klodwig‐Kirstein, Jana Schwieger, Michaela Kreienmeyer, Verena Scheper, Athanasia Warnecke, Nina Ehlert, Peter Behrens   +10 more
wiley   +1 more source

Editorial: Psychrotolerant microbes: ecological adaptations and biotechnological potential. [PDF]

Front Microbiol
Pandey A, Sharma A, Leiva Poveda S.
europepmc   +1 more source

An Electrostatic Method for 3D Extrusion of Micron‐Sized Conductive Structures for Sensing Applications

Advanced Materials Technologies, EarlyView.
In this study, a highly conductive polymer ink was developed and printed using a high‐resolution 3D printing technique. The printed structures showed excellent electrical performance and fine detail. These features make them suitable for biosensing applications, enabling accurate detection and improved device performance in compact and customizable ...
Farnaz Rezaei, Cacie McDorman, Rickard Shen, Stefan Johansson   +3 more
wiley   +1 more source

Strengthening networks in Arctic health research and education through mentorship and collaboration. [PDF]

Int J Circumpolar Health
Ingemann C, Akearok GH, Crawford A, Cueva K, Drossos A, Emelyanova A, Fairman K, Hansen KL, Koch A, Mulvad G, Olesen I, Rautio A, Rink E, Rönkä AR, Stoor JPA, Larsen CV.   +15 more
europepmc   +1 more source

A Cryopreservation‐Based Supply Chain Strategy for Extrusion Bioprinting in Space

Advanced Materials Technologies, EarlyView.
Extrusion bioprinting on crewed space platforms requires a bioink that stays functional along the logistic chain. Here, cells and biomaterial ink travel separately, the cells cryopreserved and the ink cold stored, and are combined only minutes before printing.
Johannes Windisch, Max von Witzleben, Richard Frank Richter, Finn Dani, Constantin Greil, Sarah Duin, Anja Lode, Michael Gelinsky   +7 more
wiley   +1 more source

Individualized radiotherapy of bone metastases from prostate cancer: time trends and 5-year survival results. [PDF]

Strahlenther Onkol
Nieder C, Stanisavljevic L, Haukland EC, Mannsåker B, Fajth B, Dalhaug A.   +5 more
europepmc   +1 more source

Microfluidic Droplet Plate Preserving Single Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Morphology and Function

Advanced Materials Technologies, EarlyView.
We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang, Rachel P. White, Yashasvi Tharani, Michael A. Finocchiaro, Leona M. Ripple, Maksymilian Prondzynski, Tania Konry, Vassilios J. Bezzerides   +7 more
wiley   +1 more source

Analyses of eye lens stable isotopes across ontogeny of trophically diverse freshwater salmonids. [PDF]

PLoS One
Schumacher GT, Peebles EB, Furey NB, Kinnison MT, Kronisch GR, Murphy CA.   +5 more
europepmc   +1 more source

In‐House Manufacturing of 3D ECM Culture Chips via Vacuum Thermoforming for Enhanced Imaging Applications

Advanced Materials Technologies, EarlyView.
Desktop vacuum thermoforming enables rapid, low‐cost fabrication of 96‐channel polystyrene culture chips with very thin imaging interfaces. The resulting platform supports cell lines, primary cells, and patient‐derived organoids, and enables high‐resolution confocal microscopy and single‐cell visualization, providing an accessible approach for advanced
Aleksandra Fomina, Adam Tam, Jennifer Lam, Nila C. Wu, Nancy T. Li, Alison P. McGuigan   +5 more
wiley   +1 more source