Results 221 to 230 of about 2,216,394 (334)

Highly pathogenic avian influenza virus (H5N5) detected in an Atlantic walrus (<i>Odobenus rosmarus rosmarus</i>) in the Svalbard Archipelago, Norway, 2023. [PDF]

Emerg Microbes Infect
Postel A, Gremmel N, Lydersen C, Kovacs KM, Schick LA, Siebert U, Nymo IH, Becher P.   +7 more
europepmc   +1 more source

Imiquimod‐Loaded Phospholipid‐Free Small Unilamellar Vesicles Activate the Tumor Immune Microenvironment to Treat Liver Cancer and Liver Metastases

Advanced Healthcare Materials, EarlyView.
Imiquimod‐loaded nanoparticles (PFSUV‐IMQ) are found to decrease liver metastasis and liver tumor burden when administered intravenously. Flow cytometry, RNA‐seq and various experiments show that the anti‐tumor response is immune‐mediated by activating dendritic cells resulting in increased CD8 T cell infiltration and activity.
Vanessa Chan, Hsin‐Mei Lee, Haruka Takata, Sheng‐Liang Cheng, Yu‐Ting Yen, Lisa Pfeifer, Luke Rushton, Po‐Han Chao, Feng Zhao, Chun Yat Ong, Nojoud Al‐Fayez, Tatsuhiro Ishida, Yunching Chen, Shyh‐Dar Li   +13 more
wiley   +1 more source

Healthcare delivery in the arctic-telehealth prospects. [PDF]

Int J Circumpolar Health
Hayoun Y, Gannot I.
europepmc   +1 more source

Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery

Advanced Healthcare Materials, EarlyView.
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang, Yue Hui, Zichao Guo, Dawei Liu, Yun Liu, Huajian Gao, Chun‐Xia Zhao   +6 more
wiley   +1 more source

Effect of long-term azithromycin treatment on gut microbial diversity in children and adolescents with HIV-associated chronic lung disease. [PDF]

EBioMedicine
Flygel TT, Bargheet A, Abotsi RE, Claassen-Weitz S, Simms V, Hjerde E, Mwaikono KS, Mchugh G, Hameiri-Bowen D, Pettersen VK, Ferrand RA, Nicol M, Cavanagh JP, Flaegstad T, Sovershaeva E.   +14 more
europepmc   +1 more source

DNA Barcoding‐Enabled Tracking of Lipid Nanoparticles: Drug‐Loading‐Dependent Biodistribution and Tumor Microenvironment Targeting

Advanced Healthcare Materials, EarlyView.
In this study, lipid nanoparticles are tracked in vivo using DNA barcodes to determine how varying drug loadings affect their delivery behaviors in mice. A cost‐effective strategy is developed for simultaneously monitoring the biodistribution of a library of lipid nanoparticles (LNPs).
Letao Xu, Rui Chen, Xing Wang, Dawei Liu, Yun liu, Chun‐Xia Zhao   +5 more
wiley   +1 more source

Detection of canine distemper virus in wildlife in Italy (2022-2024). [PDF]

Front Vet Sci
Alfano F, Lucibelli MG, D'Alessio N, Auriemma C, Rea S, Sgroi G, Lucente MS, Pellegrini F, Diakoudi G, De Carlo E, Decaro N, Lanave G, Martella V, Fusco G.   +13 more
europepmc   +1 more source

Printing and Rerouting of Elastic and Protease Responsive Shape Memory Hydrogel Filaments

Advanced Healthcare Materials, EarlyView.
A biofabrication strategy, Rerouting of Free‐Floating Suspended Hydrogel Filaments (REFRESH), is developed enabling the printing of highly elastic, reconfigurable protease‐responsive hydrogel filaments with shape memory properties. The filaments can be manually braided, knotted, and rerouted to create intricate cell‐laden 3D architectures, expanding ...
Philip Lifwergren, Viktoria Schoen, Sajjad Naeimipour, Lalit Khare, Anna Wunder, Hanna Blom, Jose G. Martinez, Pierfrancesco Pagella, Anders Fridberger, Johan Junker, Daniel Aili   +10 more
wiley   +1 more source

Genetic architecture in Greenland is shaped by demography, structure and selection. [PDF]

Nature
Stæger FF, Andersen MK, Li Z, Hjerresen JP, He S, Santander CG, Jensen RT, Rex KF, Thuesen ACB, Hanghøj K, Seiding IH, Jørsboe E, Stinson SE, Rasmussen MS, Balboa RF, Larsen CVL, Bjerregaard P, Schubert M, Meisner J, Linneberg A, Grarup N, Zeggini E, Nielsen R, Jørgensen ME, Hansen T, Moltke I, Albrechtsen A.   +26 more
europepmc   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source