Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang+12 more
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Methodologies and challenges in Arctic human health risk assessment: case studies and evaluation of current practices. [PDF]
Abass K+6 more
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In this study, lipid nanoparticles are tracked in vivo using DNA barcodes to determine how varying drug loadings affect their delivery behaviors in mice. A cost‐effective strategy is developed for simultaneously monitoring the biodistribution of a library of lipid nanoparticles (LNPs).
Letao Xu+5 more
wiley +1 more source
Erratum to "Discordant Results Between Creatinine- and Cystatin C-based Equations for Estimating GFR" [<i>Kidney International Reports</i> Volume 10, Issue 4, April 2025, Pages 1248-1259]. [PDF]
Delanaye P+28 more
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This study develops 3D‐printed Mg‐MC/PLGA scaffolds with varying Mg concentrations (0–20%). The 5% Mg scaffold shows optimal cytocompatibility, osteogenic activity in vitro, and significantly enhances bone regeneration in rabbits, improving bone volume and mechanical strength.
Shihang Liu+9 more
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AMY1 gene copy number associated with xerostomia and Sjögren's syndrome: a cross-sectional study. [PDF]
Stankeviciene I+8 more
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Charge‐opposed reduced graphene oxide fillers are co‐integrated into biopolymeric nanocomposite scaffolds, synergistically enhance osteogenesis. Multiscale characterization reveals how surface chemistry and porosity dictate ectopic mineral architecture.
George Mihail Vlăsceanu+8 more
wiley +1 more source
Experimental pain tolerance is associated with dental anxiety- the Tromsø study 2015-2016. [PDF]
Nermo H+5 more
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PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall+14 more
wiley +1 more source
Unplanned transfers from wards to intensive care units: how well does NEWS identify patients in need of urgent escalation of care? [PDF]
Torvik MA, Nymo SH, Nymo SH, Ofstad EH.
europepmc +1 more source