Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
The Main Geohazards in the Russian Sector of the Arctic Ocean
The Arctic region, including vast shelf zones, has enormous resource and transport potential and is currently key to Russia’s strategic development. This region is promising and attractive for the intensification of global economic activity.
Artem A. Krylov +7 more
doaj +1 more source
Hydrographic Feature Variation Caused Pronounced Differences in Planktonic Ciliate Community in the Pacific Arctic Region in the Summer of 2016 and 2019. [PDF]
Wang C +6 more
europepmc +1 more source
Civilian Power Europe in the Arctic: How Far Can the European Union Go North? College of Europe EU Diplomacy Paper 01/2015 [PDF]
The EU Arctic policy, initiated in the European Commission’s Communication “The European Union and the Arctic region” in 2008, was created to respond to the rising expectations that the European Union would have a bigger stake in this region which was ...
Kobza, Piotr
core
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
The end of the post-Cold War in the Arctic
Trans-boundary cooperation by states, indigenous peoples and sub-national governments as well as region-building in the Arctic region has been so successful that the region is peaceful with high stability.
Lassi Heininen
doaj
SAM 2 measurements of the polar stratospheric aerosol, volume 8 [PDF]
The Stratospheric Aerosol Measurement (SAM) 2 sensor aboard Nimbus 7 is providing extinction measurements of Antarctic and Arctic stratospheric aerosols with a vertical resolution of 1 km.
Brandl, D., Mccormick, M. P.
core +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
A Sino-Russian cooperation in the Arctic region in the 21st century
Since the onset of the war in Ukraine, cooperation between China and Russia has been steadily increasing, and the Arctic region is no exception. In fact, the available evidence suggests a strong mutual understanding between the two countries in this area.
Céline Rodrigues
doaj +1 more source

