Results 41 to 50 of about 12,416 (266)

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Arctic Tourism in the Barents Sea Region: Current Situation and Boundaries of the Possible

Арктика и Север, 2020
The article discusses current trends in the development of the Arctic zone of the Russian Federation (AZRF) and the peculiarities in the Arctic tourism organization.
Dmitriy V. SEVASTYANOV
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Major demographic tendencies of the Arctic and sub-arctic zone of Russia

Yakut Medical Journal, 2019
№2(66) (2019)
K.V. Shelygin, Y.A. Sumarokov, S.I. Malyavskaya   +2 more
openaire   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Initial colonization of the Arctic zone

Comptes Rendus Palevol, 2006
Abstract Human colonization of the Arctic zone constitutes one of the most beautiful illustrations of the thesis according which human history, particularly in its early stages, represents a continuum of adaptations. The study of archaeological sites of North Fennoscandia has brought numerous evidences since the Mesolithic period.
openaire   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Status and trends in the structure of Arctic benthic food webs [PDF]

Polar Research, 2015
Ongoing climate warming is causing a dramatic loss of sea ice in the Arctic Ocean, and it is projected that the Arctic Ocean will become seasonally ice-free by 2040.
Monika Kędra, Charlotte Moritz, Emily S. Choy, Carmen David, Renate Degen, Steven Duerksen, Ingrid Ellingsen, Barbara Górska, Jacqueline M. Grebmeier, Dubrava Kirievskaya, Dick van Oevelen, Kasia Piwosz, Annette Samuelsen, Jan Marcin Węsławski   +13 more
doaj   +1 more source

Pathogenetic assessment of external respiratory function disturbance and is interrelation with BDNF gene polymorphism in military servicemen in extreme conditions of the Arctic zone

Российская Арктика, 2023
Relevance. To date, the etiopathogenesis of polar hypoxia and its relationship with polymorphismes genes have not been fully studied. The aim of the study is to study the pathogenesis of ventilation disorders and polar hypoxia and their relationship ...
Lemeshchenko A.V., Gurina O.I., Makarov A.B., Berg D.V.   +3 more
doaj   +1 more source

Morphogenetic classification of the Arctic coastal zone [PDF]

Geo-Marine Letters, 2004
Arctic coastal evolution is the result of interactions between exogenic and endogenic processes. In the arctic region, this evolution differs from that in other areas of the world’s oceans as a result of interactions between modern wave and ice factors, and the influences of glaciations and large-scale sea level changes in the past. Geologic structure,
S. L. Nikiforov, Yu A. Pavlidis, V. Rachold, M. N. Grigoryev, F. M. Rivkin, N. V. Ivanova, M. M. Koreisha   +6 more
openaire   +1 more source