Acute respiratory distress syndrome (ARDS) is frequently associated with sepsis. ARDS and sepsis exhibit a common pathobiology, namely excessive inflammation. Corticosteroids are powerful anti-inflammatory agents that are routinely used in septic shock and in oxygen-dependent SARS-CoV-2 related acute respiratory failure.
Kuperminc, Emmanuelle +3 more
openaire +5 more sources
The Effect of ARDS on Survival: Do Patients Die From ARDS or With ARDS? [PDF]
Objective: To investigate the contribution of acute respiratory distress syndrome (ARDS) in of itself to mortality among ventilated patients. Design and Setting: A longitudinal retrospective study of ventilated intensive care unit (ICU)
Lior Fuchs +8 more
openaire +3 more sources
4DPRR- Index for predicting mortality in COVID-19 ARDS [PDF]
Background Mortality in ARDS was reduced significantly after the introduction of the low tidal volume ventilation strategy. It has been recently shown that lung-protective ventilation strategies should primarily target driving pressure rather than Vt ...
PL Gautam, Gunchan Paul, M. Ravi Krishna
core +1 more source
Epidemiology and outcomes of early-onset AKI in COVID-19-related ARDS in comparison with non-COVID-19-related ARDS: insights from two prospective global cohort studies [PDF]
BACKGROUND: Acute kidney injury (AKI) is a frequent and severe complication of both COVID-19-related acute respiratory distress syndrome (ARDS) and non-COVID-19-related ARDS. The COVID-19 Critical Care Consortium (CCCC) has generated a global data set on
Daniel Brodie +45 more
core +1 more source
The discovery of biological subphenotypes in ARDS: a novel approach to targeted medicine? [PDF]
The acute respiratory distress syndrome (ARDS) is a severe lung disorder with a high morbidity and mortality which affects all age groups. Despite active research with intense, ongoing attempts in developing pharmacological agents to treat ARDS, its ...
Fraser, J +5 more
core +1 more source
COVID-19 ARDS Patients Successfully Extubated to Extubated to High-Flow Nasal Cannula Oxygen Therapy: A Retrospective Analysis [PDF]
Objective:The acute respiratory distress syndrome (ARDS)-associated coronavirus disease-2019 (COVID-19), caused by the highly contagious severe acute respiratory syndrome coronavirus 2 novel coronavirus, is a major cause of death during the pandemic ...
Özlem Polat +9 more
core +1 more source
Superimposed high-frequency jet ventilation combined with continuous positive airway pressure/assisted spontaneous breathing improves oxygenation in patients with H1N1-associated ARDS [PDF]
Background: Numerous cases of swine-origin 2009 H1N1 influenza A virus (H1N1)-associated acute respiratory distress syndrome (ARDS) bridged by extracorporeal membrane oxygenation (ECMO) therapy have been reported; however, complication rates are high. We
Wolf, Timo +15 more
core +1 more source
Cisplatin-Based Chemotherapy for Pulmonary Metastasized Germ Cell Tumors of the Testis - Be Aware of Acute Respiratory Distress Syndrome [PDF]
Background: Cisplatin-based combination chemotherapy is regarded as standard of care for patients with advanced germ cell tumors. In patients with lung metastases and a high tumor load, an association between induction chemotherapy and the development of
Parhofer, Klaus G. +6 more
core +1 more source
Promises and challenges of personalized medicine to guide ARDS therapy [PDF]
Identifying new effective treatments for the acute respiratory distress syndrome (ARDS), including COVID-19 ARDS, remains a challenge. The field of ARDS investigation is moving increasingly toward innovative approaches such as the personalization of ...
Wick, Katherine D +16 more
core +1 more source
Background and Aims: We describe the epidemiological and clinical characteristics, and 28 day outcome of critically ill COVID-19 patients admitted to a tertiary care centre in India.
Rupavath Ramkumar +10 more
doaj +1 more source

