Results 111 to 120 of about 23,210,390 (344)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Oshibana Aksesoris oleh Mahasiswa Biologi UMA (Universitas Medan Area
, 2018 video ini memberikan informasi tentang oshibana (dalam bahasa jepang) yang artinya kreasi bunga dan aksesoris menggunakan limbah bekas yang dilakukan oleh mahasiswa fakultas biologi universitas medan ...
Universitas Medan Area
core +1 more source
Gerak Jalan Santai HUT RI 73 Civitas Akademik Universitas Medan Area
, 2018 Memperingati Hari Ulang Tahun (HUT) Republik Indonesia ke-73, segenap civitas akademika Uiversitas Medan Area (UMA) dan siswa/i SMK/SMA/Sederajat se-kota medan mengikuti acara gerak jalan santai, Kamis (16/08).
Humas, Universitas Medan Area
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
ABOUT THE NEW VERSION OF THE “ICE” SOFTWARE PACKAGE
InterCarto. InterGIS, 2017 The paper describes the new version (1.2) of the “Ice” software designed for calculating the sea ice area of different cohesion according to pentad (once in five days) archival maps of the ice cover of the Sea of Okhotsk and the Sea of Japan, based on ...
I. V. Shumilov +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source