Results 181 to 190 of about 23,210,390 (344)

Histological analysis of the spatio-temporal development of porcine knee cartilage in embryonic and early postnatal stages. [PDF]

Animal Model Exp Med
Nie Y, Wang K, Wang X, Jing J, Liang Z, Yan G, Guo WF, Zhang M, Zhang W, Xiang L.   +9 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

A Chromium Terephthalate-Based Solid with Unusually Large Pore Volumes and Surface Area

Science, 2005
G. Férey, C. Mellot-Draznieks, C. Serre, F. Millange, J. Dutour, S. Surblé, I. Margiolaki   +6 more
semanticscholar   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

The short-term impact of ambient air pollution on years of life lost from cancer in Pudong New Area, Shanghai: A time series study. [PDF]

PLoS One
Zhong X, Sheng J, Chen Y, Chen H, Han S, Qu X, Sun L, Wang S, Hu C, Hao L.   +9 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Vulture populations, seasonal dynamics, and conservation threats in the Urban landscape: a case study in Jimma, Southwest Ethiopia. [PDF]

BMC Zool
Deressa DF, Alemu T, Aticho A, Gutema TM.   +3 more
europepmc   +1 more source

Trauma and posttraumatic stress disorder in the community: the 1996 Detroit Area Survey of Trauma.

Archives of General Psychiatry, 1998
N. Breslau, R. Kessler, H. Chilcoat, L. Schultz, G. C. Davis, P. Andreski   +5 more
semanticscholar   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

New to Science: Insect Discoveries from Long-Term Monitoring in Terrestrial Protected Areas in Abu Dhabi, UAE. [PDF]

Insects
Saji A, Rashdi ZSA, Ahmed S, Ali Mohamed A, Al Dhaheri SS.   +4 more
europepmc   +1 more source