Results 221 to 230 of about 20,707,555 (353)

A Simple Generalisation of the Area Under the ROC Curve for Multiple Class Classification Problems

Machine-mediated learning, 2001
D. Hand, R. Till
semanticscholar   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Comparative analysis of whole-slide scanner tissue detection algorithms: Implications for scan area, scan time, and file size in high-volume digital pathology workflows. [PDF]

J Pathol Inform
Bilal KH, Gelfant K, Manzo A, Reuter VE, Hameed M, Hanna MG, Ardon O.   +6 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Assessment of boron accumulation and pollution levels and their relation to soil classification. [PDF]

Environ Geochem Health
Koca YK, Aytop H, Yılmaz CH, Demir ÖF, Sünbül MR, Erayman HM, Dikici H.   +6 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Directional Analysis of Residual RPE Area Loss in the Natural History of Choroideremia. [PDF]

Invest Ophthalmol Vis Sci
Chujo S, Abbasgholizadeh R, Alhelaly M, Nittala MG, Quarta A, Chung YC, Kwak H, Soylu C, Rattu R, Huang J, Corradetti G, Velaga S, Forte P, Uji A, Sadda SR.   +14 more
europepmc   +1 more source

Area V1

Scholarpedia, 2012
openaire   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source