In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Pathogenic Variants in HEPACAM Alter Protein Localization and Interactome in Astrocytes of the Developing Mouse Cortex. [PDF]
Lewis RW +10 more
europepmc +1 more source
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Climatic and Hydrological Changes Drive Contemporary Fire Regime Transitions in the World's Largest Wetland. [PDF]
Barros-Rosa L +17 more
europepmc +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
CLSM-guided imaging provides new insights into position-dependent limitations of endodontic disinfection. [PDF]
Böcher S +4 more
europepmc +1 more source
Structural controls on gold deposits in the Egyptian Nubian Shield: insights from the Atalla-Sid Shear Belt, Central Eastern Desert, Egypt. [PDF]
Hamimi Z +4 more
europepmc +1 more source
Mahasiswa Universitas Medan Area Merubah Limbah Plastik jadi BBM
Universitas Medan Area
core +1 more source
Thermal Stress and Habitat Loss: Assessing the Vulnerability of <i>Potamon fluviatile</i> (Decapoda: Potamidae) to Climate Change in Italy. [PDF]
Ghasemian Sorboni S +3 more
europepmc +1 more source

