Results 81 to 90 of about 19,311,004 (300)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Urological Science, 2014 Objective: The authors aim to analyze age, geographic, and seasonal variations in the medical services utilization of patients with varicocele in Taiwan using a population-based study. Methods: Between 2001 and 2008, a retrospective nationwide population-
Wen-Liang Liu +5 more
doaj +1 more source
Euro area governance: What went wrong in the euro area? How to repair it? [PDF]
Bruegel Director Jean Pisani-Ferry focuses on the institutional response to the euro area crisis with the Van Rompuy Task Force being set up to reform economic governance.
Jean Pisani-Ferry
core +1 more source
21st December Special Board Meeting (401 KB) [PDF]
, 2000 NAHB ...
Northern Area Health Board (NAHB)
core
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Repenser la question migratoire : migrations, inégalités multisituées et individuation
Sociologies, 2011 The author invites us to reconsider the migration issue from an innovative conceptual space that combines “multi-located inequalities”, migration experiences & competencies, as well as recognition concepts.
Laurence Roulleau-Berger
doaj
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
, 2019 A flag area measure on an $n$-dimensional euclidean vector space is a continuous translation-invariant valuation with values in the space of signed measures on the flag manifold consisting of a unit vector $v$ and a $(p+1)$-dimensional linear subspace ...
Abardia-Evéquoz, Judit +2 more
core +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source