Results 171 to 180 of about 222,748 (268)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

[Hyperuricaemia as a cardiovascular risk factor]. [PDF]

Aten Primaria
Álvarez Lozano B, Deniel-Rosanas J, Ortiz Arissó B, Roura-Poch P.   +3 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Rare upside of climate-induced phenological changes: Gentoo penguins (Pygoscelis papua) avoid heat events at Martillo Isl., Tierra del Fuego, Argentina. [PDF]

PLoS One
Harris S, Juárez Martínez I, Hart T, Raya Rey A.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

WCN24-1662 EPIDEMIOLOGY OF CHRONIC KIDNEY DISEASE (CKD) WITH A GENDER APPROACH IN CHILDREN IN 2 REFERENCE HOSPITALS IN PARAGUAY

Kidney International Reports
NIDIA ELIZABETH GOMEZ MOLINAS, Avelina Troche, Domingo Avalos, Marlene Martinez, Teresita Adorno, Fabiola Lezcano, Nilsa Nuñez, Mearlyn Basabe, Cynthia Duarte, Claudia Gamarra   +9 more
doaj   +1 more source

Modified Del Nido Cardioplegia with a 1:4 Crystalloid-to-Blood Ratio Versus Blood-Based St. Thomas Cardioplegia in Isolated Aortic Valve Replacement. [PDF]

J Cardiovasc Dev Dis
Jakub P, Toporcer T, Marcin M, Trebišovský M, Bereš A, Homola M, Lukačín Š, Kolesár A.   +7 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Sociodemographic determinants of health care in heart failure mortality in Mexico, 019 and 2023. [PDF]

Rev Bras Epidemiol
Campuzano JC, Rodríguez JM, Chaparro PE, Urrego DC, Hernández A.   +4 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source