Results 191 to 200 of about 4,100,602 (260)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Computer-based tree drawing test in adolescents and adults with depression. [PDF]

Front Psychiatry
Jin H, Liu Y, Li Y, Liu L, Gao L, Liu W, Zhang Y, Liu G.   +7 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Sorption of Antibiotics in Sewage Sludge: Distribution Coefficients, Sludge Characteristics, and Implications for Environmental Fate. [PDF]

J Xenobiot
Shin W, Kim PG, Oak MH.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Choroidal structural and perfusion characteristics across refractive groups in children. [PDF]

Front Med (Lausanne)
Liu Y, Tao G, Zhao Y, Ma M, Feng S, Qin M, Bao X.   +6 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Acute Effect of Percussive Massage on Cross-Section Area, Muscle Strength, and Late Muscle Pain of the Quadriceps Muscle Following a Fatigue Protocol in Physically Active Men: Randomized Clinical Trial. [PDF]

Physiother Res Int
da Rosa Castilho A, Aguiar AF, Ribeiro AS, Cônsolo IF, Quirino FSP, de Oliveira RF, Andraus RAC.   +6 more
europepmc   +1 more source

Effects of Selective Sphingosine-1-Phosphate Receptor 1 Agonist, TRV045, on Evoked Pain Tests: An Exploratory, Four-Way Cross-Over Study in Healthy Volunteers. [PDF]

Eur J Pain
Bakker WA, Eijsvogel P, Klaassen ES, Kim J, Chen R, Demitrack MA, Dahan A, Niesters M, Hijma HJ, Groeneveld GJ.   +9 more
europepmc   +1 more source

Evaluating reliability of automated quantitative brain morphometry from fetal T2-weighted MRI. [PDF]

Front Neurosci
Jeong S, Gondova A, Yun HJ, You S, Lagunas M, Golland P, Grant PE, Im K.   +7 more
europepmc   +1 more source