Usefulness of a novel system for measuring glucose area under the curve while screening for glucose intolerance in outpatients [PDF]
Kenya Sakamoto +12 more
openalex +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Area under the ROC Curve has the Most Consistent Evaluation for Binary Classification [PDF]
Jing Li
openalex +1 more source
A novel methodology to characterize beat-to-beat alternations in whole-cell calcium currents. [PDF]
Marimon X +3 more
europepmc +1 more source
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
From the Help Desk: Comparing Areas under Receiver Operating Characteristic Curves from Two or more Probit or Logit Models [PDF]
Mario A. Cleves
openalex +1 more source
Transfer-learning on federated observational healthcare data for prediction models using Bayesian sparse logistic regression with informed priors. [PDF]
Li KM +4 more
europepmc +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Multimodal Transformer-Based Electrocardiogram Analysis for Cardiovascular Comorbidity Detection: Model Development and Validation Study. [PDF]
Yang Z +8 more
europepmc +1 more source

