A Validated Model to Predict Severe Weight Loss in Amyotrophic Lateral Sclerosis
ABSTRACT Severe weight loss in amyotrophic lateral sclerosis (ALS) is common, multifactorial, and associated with shortened survival. Using longitudinal weight data from over 6000 patients with ALS across three cohorts, we built an accelerated failure time model to predict the risk of future severe (≥ 10%) weight loss using five single‐timepoint ...
David G. Lester+4 more
wiley +1 more source
A deep learning model for predicting radiation-induced xerostomia in patients with head and neck cancer based on multi-channel fusion. [PDF]
Lin L+9 more
europepmc +1 more source
Maximizing the Area under the ROC Curve with Decision Lists and Rule Sets
Henrik Boström
openalex +2 more sources
Real‐World Comparison of High‐Efficacy Versus Non‐High‐Efficacy Therapies in Multiple Sclerosis
ABSTRACT Objective The choice of the first disease modifying treatment (DMT) in multiple sclerosis (MS) is a topic of great interest, and whether high‐efficacy DMTs should be the first choice remains debated. We compared treatment outcomes (no evidence of disease activity [NEDA] and its components) between treatment‐naïve relapsing–remitting MS (RRMS ...
Sarmad Al‐Araji+9 more
wiley +1 more source
Machine learning algorithms to predict the risk of admission to intensive care units in HIV-infected individuals: a single-centre study. [PDF]
Li J+16 more
europepmc +1 more source
Area‐under‐the‐HbA1c‐curve above the normal range and the prediction of microvascular outcomes: an analysis of data from the Diabetes Control and Complications Trial [PDF]
Louise Maple‐Brown+2 more
openalex +1 more source
ABSTRACT Objective To evaluate the long‐term impact of early intensive treatment (EIT) versus escalation (ESC) strategies using high‐efficacy disease‐modifying therapies (HE‐DMTs) on disability progression in relapsing multiple sclerosis (RMS). Methods This observational study included 4878 RMS patients from the Italian Multiple Sclerosis Register ...
Pietro Iaffaldano+47 more
wiley +1 more source
Noninvasive prediction of Ki-67 expression in pancreatic cancer <i>via</i> contrast-enhanced ultrasound quantitative parameters: A diagnostic model study. [PDF]
Yang ZY+5 more
europepmc +1 more source
Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia+20 more
wiley +1 more source
Coronary cross-sectional area stenosis severity determined using coronary CT highly correlated with coronary functional flow reserve: a pilot study. [PDF]
Koumoto T+9 more
europepmc +1 more source