Results 121 to 130 of about 270,097 (301)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Illegal Fiscal Aids or Advance Tax Rulings? Insights and PRedictions from Starbucks and FIAT
, 2019 Countries from all over the world have traditionally relied on tax breaks to attract investments by multinational companies. Lately, some international tax competition practices have been attracting increasing criticism. In the US, for example, political
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
The chapter examines the correspondence between Gaetano Filangieri and Benjamin Franklin as an expression of a shared set of values and ideas that were fundamental to the American Constitution and the process of European integration.
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Il contributo esamina la corrispondenza tra Gaetano Filangieri e Benjamin Franklin come espressione di una sintonia di valori e idee fondamentali per la Costituzione americana e per il processo di integrazione europea.
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Språkkaféet som arena för språkträning [Elektronisk resurs]
, 2020 Genom tidigare forskning vet vi relativt mycket om skolans roll för migranters vägar in i det svenska samhället. Vi vet mindre om civilsamhällets stöd och roll i integrationsprocessen, särskilt när det gäller språklig integration.
Jansson, Gunilla,, Kunitz, Silvia
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
State Aids, Tax Rulings, and Multinational Firms: A View from Europe
, 2017 As U.S. states eagerly offer incentives in an effort to win the sweepstakes for Amazon's HQ2, it is worth revisiting the very different world in Europe.
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