Results 31 to 40 of about 6,810 (160)

Copeptin Release in Arterial Hypotension and Its Association with Severity of Disease in Critically Ill Children

Children, 2022
Low copeptin levels may indicate inadequate arginine-vasopressin release promoting arterial hypotension, whereas high copeptin concentrations may reflect disease severity.
Philipp Baumann, Verena Gotta, Andrew Atkinson, Markus Deisenberg, Martin Hersberger, Adam Roggia, Kevin Schmid, Vincenzo Cannizzaro   +7 more
doaj   +1 more source

Incidence and Treatment of Arginine Vasopressin Deficiency (Central Diabetes Insipidus) in the Setting of Brain Death and Associations with Renal Function and Hemodynamics in Organ Donors [PDF]

Journal of Clinical Medicine
Björn Nashan, Dominik Michalski, Robert Werdehausen   +2 more
exaly   +2 more sources

Effects of Tirzepatide Therapy on Arginine Vasopressin Deficiency: A Case with Reduced Desmopressin Requirement

Endocrinology Research and Practice
Arginine vasopressin deficiency (AVP-D) is a rare endocrine disorder that causes polyuria and polydipsia. The case of a 45-year-old woman with AVP-D who showed a marked reduction in urine output and desmopressin requirement after starting tirzepatide ...
Elif Yivli, Ömercan Topaloğlu
doaj   +3 more sources

Arginine vasopressin deficiency

Nature Reviews Endocrinology
Polyuria–polydipsia syndrome can be caused by central diabetes insipidus, nephrogenic diabetes insipidus or primary polydipsia. To avoid confusion with diabetes mellitus, the name ‘central diabetes insipidus’ was changed in 2022 to arginine vasopressin (AVP) deficiency and ‘nephrogenic diabetes insipidus’ was renamed as AVP resistance. To differentiate
Atila, Cihan, Refardt, Julie, Christ-Crain, Mirjam   +2 more
openaire   +3 more sources

Adipsic central diabetes insipidus as a result of neurosarcoidosis

Revista Mexicana de Endocrinología, Metabolismo y Nutrición
Sarcoidosis is a systemic multisystem inflammatory disorder of unknown etiology characterized by the presence of non-caseating granulomas. Neurosarcoidosis leads to hypothalamus- pituitary axis dysfunction, and the most common clinical manifestation is ...
Radmila Milosheska, Ivana Mickovski, Daniela Buklioska Ilijevska   +2 more
doaj   +1 more source

Physiological basis of arginine vasopressin deficiency (AVP-D, formerly central diabetes insipidus) and AVP-resistance (AVP-R, formerly nephrogenic diabetes insipidus) [PDF]

Exploration of Medicine
This review explored the physiological mechanisms underlying arginine vasopressin deficiency (AVP-D, formerly central diabetes insipidus) and AVP resistance (AVP-R, formerly nephrogenic diabetes insipidus), with a focus on water balance regulation. Vital
Osah Martins Onwuka
doaj   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

Advanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang, Shaofang He, Zhongkai Wang, Aobo Pang, Xiaoli Sun, Rongchen Liu, Fang Wang, Sisi Chen, Zhijuan Bian, Dongcheng Wei, Liuhan Wu, Siyao Zhao, Qiuting Ji, Yiqi Sun, Niying Sun, Yushinta Fujaya, Boping Tang, Kianann Tan, Daizhen Zhang, Lianfu Chen   +19 more
wiley   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Multiphase management of sodium imbalance following traumatic brain injury: a case-based review

BMC Pediatrics
Background This review article discusses a case of sodium imbalance and fluid dysregulation in a patient with traumatic brain injury (TBI), progressing through phases including mannitol-induced osmotic diuresis, arginine vasopressin deficiency (central ...
Vinson James, Laura Nimkoff
doaj   +1 more source