Results 81 to 90 of about 6,810 (160)

Untangling Mephedrone‐Induced Social Reward in Rats—The Involvement of Oxytocin and Vasopressin V1A Receptors

Genes, Brain and Behavior, Volume 25, Issue 4, August 2026.
Social context alters the neurochemical and neuropeptidergic mechanisms of mephedrone reward, revealing a dual regulation by monoamines and oxytocin/vasopressin signaling in brain regions critical for reinforcement. ABSTRACT The rewarding effects of psychostimulants are strongly influenced by social context, yet the underlying neurochemical and ...
Olga Wronikowska‐Denysiuk, Łukasz Kurach, Radosław Mlak, Dominika Przygodzka, Tymoteusz Słowik, Barbara Budzyńska   +5 more
wiley   +1 more source

History of clinical applications of desmopressin

Continence
Desmopressin is a synthetic analog of the endogenous peptide hormone arginine vasopressin, or antidiuretic hormone. The drug was initially developed in 1967 with the intention of creating a molecule that could treat central diabetes insipidus, a ...
Lennox R. Ksido, Cassandra V. Heaney, Thomas F. Monaghan, Jeffrey P. Weiss   +3 more
doaj   +1 more source

Transcriptomic changes in the jerboa supraoptic nucleus during osmotic stress: PCSK1 and PTPRN changes are conserved across desert and mesic species

Journal of Neuroendocrinology, Volume 38, Issue 8, August 2026.
Abstract The supraoptic nucleus (SON) is a hypothalamic region essential for the orchestration of osmoregulation in mammals. We sought to understand how gene expression in the SON is orchestrated in a rodent species adapted for survival in arid desert conditions.
Benjamin T. Gillard, Nabil Amor, Michael P. Greenwood, Abdulaziz N. Alagaili, David Murphy   +4 more
wiley   +1 more source

A rare diagnosis of Langerhans cell histiocytosis made on thyroid histology with coexisting papillary thyroid cancer and AVP deficiency

Endocrinology, Diabetes & Metabolism Case Reports
A 48-year-old Asian male, presented to the hospital for an elective total thyroidectomy in the context of 6.3 cm thyroid nodule. The fine needle aspiration cytology of the nodule confirmed papillary thyroid cancer (PTC) with some atypical histiocytes. He
R K Dharmaputra, C M Piesse, S Chaubey, A K Sinha, H C Chiam   +4 more
doaj   +1 more source

Arginine Vasopressin-Independent Mechanism of Impaired Water Excretion in a Patient with Sarcoidosis Complicated by Central Diabetes Insipidus and Glucocorticoid Deficiency

Case Reports in Medicine, 2011
A 28-year-old man was admitted to our hospital because of reduced livido and increased fatigability. Four months before admission, he noticed polyuria, which was gradually relieved by admission.
Katsunobu Yoshioka, Nagaaki Tanaka, Keiko Yamagami, Takeshi Inoue, Masayuki Hosoi   +4 more
doaj   +1 more source

Diagnostic difficulties in a 9-year-old boy with pituitary germinoma

Endokrynologia Polska
Not required for Clinical Vignette.
Elżbieta Moszczyńska, Katarzyna Pasternak-Pietrzak, Aleksandra Tutka, Paulina Chodnicka, Marta Perek-Polnik, Maria Maksymowicz, Grzegorz Zieliński   +6 more
doaj   +1 more source

Endocrine Outcome and Quality of Life After Transsphenoidal Resection of Pituitary Adenoma—A Prospective Randomized Single-Blinded Study Comparing Endoscopic Versus Microscopic Resection

Neurology International
Background: Endoscopic pituitary surgery might yield better endocrine outcomes compared to microscopic resection. We conducted a prospective, randomized, single-blinded study to compare the endocrine outcome and quality of life (QoL) of patients with ...
Andrej Pala, Nadja Grübel, Benjamin Mayer, Ralf Becker, Fabian Sommer, Bernd Schmitz, Gwendolin Etzrodt-Walter, Christian Rainer Wirtz, Michal Hlavac   +8 more
doaj   +1 more source

Central Diabetes Insipidus in Father and Son Linked to a Rare Variant: A Case Report

Biomedicine Hub
Introduction: Central diabetes insipidus (CDI) is a rare disorder caused by a deficiency in the secretion of arginine vasopressin (AVP) from the posterior pituitary. It can be either acquired or congenital, often due to genetic factors, and is
Paula Bruna Mattos Coelho Araujo, Luiz Filipe Rocha de Sá, Rafaela Sousa, Darine Villela, Thereza Taylanne Souza Loureiro Cavalcanti, Michele Patricia Migliavacca, Marilia Martins Guimaraes, Micheline Abreu Rayol Souza, Erika Naliato, Mariana Botelho, João Bosco Nascimento, Mirna Sanchez Carvallo, Pedro Martins Viveiros, Delmar Muniz Lourenço Junior, Rosita Fontes, Alice Helena Dutra Violante   +15 more
doaj   +1 more source

Glucagon-stimulated copeptin response in children: a proof-of-concept study

Frontiers in Endocrinology
PurposeThe diagnostic workup of polyuria-polydipsia syndrome (PPS) is not well-established in children and adolescents, and several non-osmotic copeptin-stimulating agents have been investigated.
Rita Indirli, Rita Indirli, Federico Giacchetti, Eriselda Profka, Eriselda Profka, Giulia Rodari, Iulia Petria, Iulia Petria, Maura Arosio, Maura Arosio, Claudia Giavoli, Claudia Giavoli, Giovanna Mantovani, Giovanna Mantovani, Emanuele Ferrante   +14 more
doaj   +1 more source

Oxytocin levels in response to CRH administration in hypopituitarism and hypothalamic damage: a randomized, crossover, placebo-controlled trial

Scientific Reports
Increasing evidence supports the presence of oxytocin deficiency (OXT-D) in patients with hypopituitarism and hypothalamic damage (HHD), that might be associated with neuropsychological deficits and sexual dysfunction, leading to worse quality of life ...
Queralt Asla, Maite Garrido, Eulàlia Urgell, Sílvia Terzan, Alicia Santos, Mercè Fernández, Nimmy Varghese, Cihan Atila, Anna Calabrese, Betina Biagetti, Franziska Plessow, Ignasi Gich, Mirjam Christ-Crain, Anne Eckert, Susan M. Webb, Elizabeth A. Lawson, Anna Aulinas   +16 more
doaj   +1 more source