Results 111 to 120 of about 144,966 (254)

Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells

International Journal of Cancer, Volume 158, Issue 10, Page 2641-2649, 15 May 2026.
What's New? Exercise releases bioactive molecules into the bloodstream that can directly slow cancer cell growth. In colon cancer, this may help limit disease progression. Here, using colon cancer cells, the authors investigated the effects of exercise‐conditioned human serum on DNA repair mechanisms. Notably, acute exercise in humans elicited systemic
Samuel T. Orange, Emily Dodd, Sharanya Nath, Hannah Bowden, Alastair R. Jordan, Hannah Tweddle, Ann Hedley, Ifeoma Chukwuma, Ian Hickson, Sweta Sharma Saha   +9 more
wiley   +1 more source

In silico peptide self‐assembly reveals the importance of N‐terminal motifs and the inhibition mechanism of the mutation L38M in α‐synuclein fibrillation

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Alpha‐synuclein (αSyn) is a presynaptic protein associated with several neurodegenerative diseases. While the non‐amyloid component (NAC) region of the αSyn sequence (residues 65–90) forms the core of all αSyn fibrils, recent findings suggest that the flanking regions play a key role in initiating or preventing amyloid formation. Two motifs in
Van T. T. Nguyen, Sabine M. Ulamec, David J. Brockwell, Sheena E. Radford, Carol K. Hall   +4 more
wiley   +1 more source

Understanding cell‐penetrating peptide mechanisms using computational electrophysiology simulations

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Cell‐penetrating peptides (CPPs) can enter cells without inducing cytotoxicity and can be coupled with cargo molecules to be used to deliver drugs, DNA, or nanoparticles into cells. The peptide‐membrane interactions driving the internalization mechanism are not completely understood. In this study, we introduce Computational Electrophysiology (
Eric Catalina‐Hernandez, Marcel Aguilella‐Arzo, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +3 more
wiley   +1 more source

Contribution of Unconventional Mesoscale Eddies to Surface Poleward Heat Flux in the Southern Ocean Over the Past Three Decades

Geophysical Research Letters, Volume 53, Issue 6, 28 March 2026.
Abstract Mesoscale eddies play a key role in transporting heat poleward across the Antarctic Circumpolar Current (ACC). In addition to conventional eddies (warm‐core anticyclones and cold‐core cyclones), recent studies have detected a significant number of unconventional eddies at the surface (cold‐core anticyclones and warm‐core cyclones).
Shimin Yuan, Ruiyi Chen, Yiyong Luo
wiley   +1 more source

Submesoscale Vertical Heat Flux Amplifies a Cross‐Scale Positive Feedback in the Western Arabian Sea

Geophysical Research Letters, Volume 53, Issue 6, 28 March 2026.
Abstract High‐resolution simulations reveal that summer monsoon‐induced upwelling in the western Arabian Sea triggers vigorous submesoscale vertical heat flux (SVHF), challenging the conventional view of winter‐dominant submesoscale activity in open‐ocean settings.
Chaoliang Li, Peng Zhan
wiley   +1 more source

Modeling Variability in Vertical Profiles of Particulate Organic Carbon Flux

Geophysical Research Letters, Volume 53, Issue 6, 28 March 2026.
Abstract The vertical flux of particulate organic carbon (POC) from the surface to the deep ocean regulates the ocean carbon uptake, with implications for the Earth's carbon cycle. It is debated in the literature what functional form best describes the attenuation of this flux with depth.
Katherine Taylor, Raffaele Ferrari, B. B. Cael   +2 more
wiley   +1 more source

Prolonged Low‐Salinity in the Eastern Arabian Sea Associated With the 2020–2023 Triple‐Dip La Niña

Geophysical Research Letters, Volume 53, Issue 5, 16 March 2026.
Abstract Prolonged low salinity was observed in the eastern Arabian Sea (EAS) from autumn 2020 to autumn 2023, closely associated with the 2020–2023 triple‐dip La Niña. Oceanic planetary wave bridge was a key driver of the extremely low salinity during winter, whereas freshwater flux remained an important contributor in other seasons.
Hua Zheng, Lisuo Hu, Yue Yu, Ruibin Ding, Xinyang Wang, Hanshi Wang, Kun Zhang, Deng Zhang, Binjie Wu, Ying Jin, Tao Zhang   +10 more
wiley   +1 more source

Argos

Journal of Association of Arab Universities for Tourism and Hospitality
We present the modeling of an AI system named ARGOS to classify free legal aid requests in the Court of Justice of Espírito Santo (TJES). The model replicates the decision-making pattern of a judge from the 6th Civil Court of Vila Velha, developed within Challenge 16 of PitchGovES by Atlas.IA, promoted by the State Management Laboratory of Espírito ...
openaire   +2 more sources

Overturning Circulation of the North Atlantic Subtropical Gyre Computed in Density Coordinates at 26°N

Geophysical Research Letters, Volume 53, Issue 5, 16 March 2026.
Abstract The RAPID‐MOCHA‐WBTS array in the subtropical gyre of the North Atlantic has measured the Atlantic Meridional Overturning Circulation (AMOC) and the overturning streamfunction in depth coordinates since 2004. Here we show that the overturning streamfunction in density coordinates can be estimated by combining data from the RAPID‐MOCHA‐WBTS ...
D. A. Smeed, W. E. Johns, R. H. Smith, T. Petit, E. L. McDonagh, D. Rayner, D. L. Volkov, S. Elipot, J. B. Kajtar, B. A. King, Y. L. Firing, B. I. Moat   +11 more
wiley   +1 more source

North Pacific Model Biases Influence Kuroshio Extension Atmospheric Circulation Patterns

Geophysical Research Letters, Volume 53, Issue 5, 16 March 2026.
Abstract The Kuroshio Extension (KE) system significantly impacts decadal North Pacific climate variability by modulating downstream atmospheric circulation patterns. Using satellite‐derived and reanalysis products, and simulations from the High Resolution Model Intercomparison Project within the Coupled Model Intercomparison Project Phase 6, we ...
Se‐Yong Song, Samantha Stevenson, Emanuele Di Lorenzo, Matthew Newman, Antonietta Capotondi, Niklas Schneider   +5 more
wiley   +1 more source